1491141-88-8

Basic information

• Product Name: N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-(2-methylphenyl)pyridine-2-carboxamide
• Synonyms: N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-(2-methylphenyl)pyridine-2-carboxamide
• CAS NO: 1491141-88-8
• Molecular Weight: 635.738
• Mol File: 1491141-88-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-(2-methylphenyl)pyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-(2-methylphenyl)pyridine-2-carboxamide(1491141-88-8)
• EPA Substance Registry System: N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]quinoline-4-yl]oxy]phenyl]-4-(2-methylphenyl)pyridine-2-carboxamide(1491141-88-8)

Safety Data

• Hazardous Substances Data: 1491141-88-8(Hazardous Substances Data)

Upstream product

• 58113-30-7 4-(3-chloropropoxy)-3-methoxyacetophenone 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 960299-67-6 3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenylamine 
• 53750-66-6 4-chloro-pyridine-2-carbonyl chloride 
• 1491141-82-2 4-chloro-N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)picolinamide 
• 16419-60-6 2-Methylphenylboronic acid 
• 960299-66-5 4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline 
• 98-98-6 2-Picolinic acid 
• 1061610-61-4 4-chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)-propoxy)quinoline 
• 1394166-09-6 6-methyloxy-7-(4-(3-chloropropoxy))-4-4-hydroxyquinoline 
• 1449763-02-3 1-(4-(3-chloropropoxy)-5-methoxy-2-nitrophenyl)-3-(dimethylamino)propyl-2-en-1-one 
• 1160707-44-7 1-[4-(3-chloropropoxy)-5-methoxy-2-nitrophenyl]ethan-1-one 

Relevant articles and documents

Quinoline compound and its preparation method and application (by machine translation)

The invention relates to the general formula I shown quinoline derivatives and their pharmaceutically acceptable salt, hydrate, solvate and prodrug, wherein substituent R1 , R2 , X, Y, Z, n has the meaning given in the specification. The invention also relates to the compounds of the general formula I has strong inhibition of c - Met kinase function, and also relates to the compounds and its pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof in the preparation of the treatment because the c - Met kinase abnormal high expression of diseases caused by the use of the medicaments, in particular in preparing and treating and/or preventing cancer of the use of the medicament. (by machine translation)