158884-42-5

Basic information

• Product Name: 2-(2,2,2-Trifluoroethyl)benzaldehyde
• CAS NO: 158884-42-5
• Molecular Weight: 188.149
• Mol File: 158884-42-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2,2,2-Trifluoroethyl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2,2-Trifluoroethyl)benzaldehyde(158884-42-5)
• EPA Substance Registry System: 2-(2,2,2-Trifluoroethyl)benzaldehyde(158884-42-5)

Safety Data

• Hazardous Substances Data: 158884-42-5(Hazardous Substances Data)

Upstream product

• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 26260-02-6 2-iodobenzaldehyde 
• 158884-39-0 2,2,2-trifluoro-1-[2-(methyl)phenyl]ethyl 4-methylbenzenesulfonate 
• 158884-40-3 1-Methyl-2-(2,2,2-trifluoroethyl)benzene 
• 341-39-9 2-methyl-α,α,α-trifluoroacetophenone 
• 438-24-4 2,2,2-trifluoro-1-(2'-methylphenyl)ethanol 
• 644-36-0 o-methylphenylacetic acid 
• 158884-41-4 1-(Bromomethyl)-2-(2,2,2-trifluoroethyl)benzene 

Downstream Products

• 158884-12-9 C₉H₆⁽²⁾HF₃N₂ 
• 158884-11-8 <2-(2,2,2-Trifluoroethyl)phenyl>diazomethane 
• 158884-43-6 2-(2,2,2-Trifluoroethyl)benzaldehyde tosylhydrazone 

Relevant articles and documents

Nickel-Catalyzed Direct Trifluoroethylation of Aryl Iodides with 1,1,1-Trifluoro-2-Iodoethane via Reductive Coupling

A nickel-catalyzed direct trifluoroethylation of aryl iodides with an industrial raw material CF3CH2I has been developed, demonstrating high efficiency, excellent functional-group compatibility, especially with large sterically hindered groups. The key to success is the combination of nickel with readily available nitrogen and phosphine ligands. The powerful potential of this strategy is further demonstrated by the late-stage modification of several derived bioactive molecules. (Figure presented.).