1642593-30-3

Basic information

• Product Name: N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide
• Synonyms: N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide
• CAS NO: 1642593-30-3
• Molecular Weight: 295.338
• Mol File: 1642593-30-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide(1642593-30-3)
• EPA Substance Registry System: N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide(1642593-30-3)

Safety Data

• Hazardous Substances Data: 1642593-30-3(Hazardous Substances Data)

Upstream product

• 36188-55-3 N-(2-(4-methoxybenzoyl)phenyl)acetamide 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 1642628-12-3 (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide 

Relevant articles and documents

Tandem Cu-catalyzed ketenimine formation and intramolecular nucleophile capture: Synthesis of 1,2-dihydro-2-iminoquinolines from 1-(o-acetamidophenyl) propargyl alcohols

The copper-catalyzed ketenimine formation reaction of 1-(o-acetamidophenyl) propargyl alcohols with various sulfonyl azides is found to undergo a concomitant intramolecular nucleophile attack to generate 1,2-dihydro-2- iminoquinolines after aromatization (via elimination of acetyl and hydroxy groups) and tautomerization. The reaction produces 4-substituted and 3,4-unsubstituted title compounds in moderate to good yields under mild reaction conditions.