1642628-12-3

Basic information

• Product Name: (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide
• Synonyms: (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide
• CAS NO: 1642628-12-3
• Molecular Weight: 404.489
• Mol File: 1642628-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide(1642628-12-3)
• EPA Substance Registry System: (E)-N-(4-(4-methoxyphenyl)quinolin-2(1H)-ylidene)-4-methylbenzenesulfonamide(1642628-12-3)

Safety Data

• Hazardous Substances Data: 1642628-12-3(Hazardous Substances Data)

Upstream product

• 36188-55-3 N-(2-(4-methoxybenzoyl)phenyl)acetamide 
• 941-55-9 4-toluenesulfonyl azide 
• 1642593-30-3 N-(2-(1-hydroxy-1-(4-methoxyphenyl)prop-2-ynyl)phenyl)acetamide 

Relevant articles and documents

Tandem Cu-catalyzed ketenimine formation and intramolecular nucleophile capture: Synthesis of 1,2-dihydro-2-iminoquinolines from 1-(o-acetamidophenyl) propargyl alcohols

The copper-catalyzed ketenimine formation reaction of 1-(o-acetamidophenyl) propargyl alcohols with various sulfonyl azides is found to undergo a concomitant intramolecular nucleophile attack to generate 1,2-dihydro-2- iminoquinolines after aromatization (via elimination of acetyl and hydroxy groups) and tautomerization. The reaction produces 4-substituted and 3,4-unsubstituted title compounds in moderate to good yields under mild reaction conditions.