1669-48-3

Basic information

• Product Name: 1-Propanone, 3-(4-nitrophenyl)-1-phenyl-
• CAS NO: 1669-48-3
• Molecular Formula: C15H13NO3
• Molecular Weight: 255.273
• Mol File: 1669-48-3.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 3-(4-nitrophenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 3-(4-nitrophenyl)-1-phenyl-(1669-48-3)
• EPA Substance Registry System: 1-Propanone, 3-(4-nitrophenyl)-1-phenyl-(1669-48-3)

Safety Data

• Hazardous Substances Data: 1669-48-3(Hazardous Substances Data)

Usage

Physical state

Yellow crystalline solid

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals; production of dyes and pigments

Biological activities

Antibacterial and antifungal properties

Hazards

Toxic and can cause irritation to skin, eyes, and respiratory system

Upstream product

• 619-73-8 4-nitrobenzyl chloride 
• 98-86-2 acetophenone 
• 636-98-6 p-nitrobenzene iodide 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 100-52-7 benzaldehyde 
• 1222-98-6 4-nitrochalcone 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 37442-45-8 ethyl 2-(hydroxy(phenyl)methyl)propenoate 
• 555-16-8 4-nitrobenzaldehdye 
• 70-11-1 α-bromoacetophenone 
• 2960-55-6 (E)-3-(4-nitrophenyl)-1-phenylprop-2-en-1-one 
• 49678-08-2 3-(4-nitrophenyl)-propenal 
• 98-80-6 phenylboronic acid 

Downstream Products

• 110655-60-2 2-(p-nitrophenyl)-1-phenylpropanol 
• 57254-06-5 2-bromo-3-(4-nitro-phenyl)-1-phenyl-propan-1-one 
• 62056-36-4 3-(4-nitro-phenyl)-1-phenyl-propan-1-ol 

Relevant articles and documents

Applications of N1-long-chain alkyl-N3-piperidine ethylimidazole salt

The invention provides applications of an N1-long-chain alkyl-N3-piperidine ethylimidazole salt, wherein the ionic liquid has surface activity and double alkalinity, and can catalyze the synthesis ofchalcone compounds. The method for synthesizing a chalcone compound under the catalysis of the ionic liquid comprises: mixing substituted benzaldehyde, substituted acetophenone and water, adding an ionic liquid, and carrying out a reaction; and after the reaction is finished, carrying out separation purification to obtain a product chalcone compound, wherein the separated catalyst-containing solution can be applied. According to the invention, the problems of strong corrosivity of composite catalyst systems such as ionic liquids/alkalis, ionic liquids/acid and the like, and high ionic liquid consumption, low yield and the like in the chalcone preparation process only using alkaline ionic liquid catalysts are overcome, and the reaction yield in the catalytic synthesis of chalcone compoundsreaches more than 85%; and the method for preparing the chalcone compound through catalysis has characteristics of easy and convenient operation, easy product separation, environmentally friendly solvent and repeated use of the catalyst.

Organocatalyzed biomimetic selective reduction of c=c double bonds of chalcones

In this article, we reported a biomimetic approach for chemoselective reduction of C=C double bonds in chalcones under metal and acid free conditions, that relies on olefin activation by hydrogen bond formation. The process requires only catalytic amount of ephedrine as hydrogen bond donor and utilizes Hantzsch esters for transfer hydrogenation.

Cobalt-Catalyzed α-Alkylation of Ketones with Primary Alcohols

An ionic cobalt-PNP complex is developed for the efficient α-alkylation of ketones with primary alcohols for the first time. A broad range of ketone and alcohol substrates were employed, leading to the isolation of alkylated ketones with yields up to 98%. The method was successfully applied to the greener synthesis of quinoline derivatives while using 2-aminobenzyl alcohol as an alkylating reagent.