16965-06-3 Usage
Description
BOC-LYS(TFA)-OH, also known as Boc-L-lysine trifluoroacetate, is a synthetic compound derived from the amino acid L-lysine. It is characterized by the presence of a butoxycarbonyl (Boc) protecting group and a trifluoroacetate (TFA) group. BOC-LYS(TFA)-OH is typically used as a building block in the synthesis of various organic molecules and has potential applications in the pharmaceutical and chemical industries.
Uses
Used in Organic Synthesis:
BOC-LYS(TFA)-OH is used as a building block for the synthesis of various organic molecules, including peptides, peptidomimetics, and other bioactive compounds. The Boc group serves as a temporary protecting group for the amino group, preventing unwanted side reactions during the synthesis process. The TFA group can be easily removed under mild acidic conditions, allowing for further functionalization of the molecule.
Used in Pharmaceutical Industry:
BOC-LYS(TFA)-OH is used as an intermediate in the development of new drugs and therapeutic agents. Its unique structure and functional groups make it a valuable component in the design and synthesis of novel pharmaceutical compounds with potential applications in various therapeutic areas, such as oncology, cardiovascular diseases, and neurological disorders.
Used in Chemical Research:
BOC-LYS(TFA)-OH is used as a research tool in the study of various chemical reactions and processes. Its reactivity and structural features make it an interesting subject for investigating new synthetic methods, reaction mechanisms, and the development of innovative chemical technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 16965-06-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,6 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 16965-06:
(7*1)+(6*6)+(5*9)+(4*6)+(3*5)+(2*0)+(1*6)=133
133 % 10 = 3
So 16965-06-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H21F3N2O5/c1-12(2,3)23-11(22)18-8(9(19)20)6-4-5-7-17-10(21)13(14,15)16/h8H,4-7H2,1-3H3,(H,17,21)(H,18,22)(H,19,20)/t8-/m0/s1
16965-06-3Relevant articles and documents
Synthesis of a radioiodinated park nucleotide analog: A new tool for antibacterial screen development
Eid, Clark N.,Nesler, Michael J.,Zia-Ebrahimi, Mohammad,Wu, Chuyn-Yeh Ernie,Yao, Raymond,Cox, Karen,Richardson, John
, p. 705 - 716 (1998)
The Park nucleotide is an important biological building block used in the construction of bacterial cell walls. Herein, we describe the synthesis of a radiolabeled Park nucleotide analog, p-iodophenoxyacyl-Ala-(D)-iso- GluLys-(D)-Ala-(D)-Ala-OH-[125
Control of lysyl oxidase activity through site-specific deuteration of lysine
Pestov, Nikolay B.,Okkelman, Irina A.,Shmanai, Vadim V.,Hurski, Alaksiej L.,Giaccia, Amato J.,Shchepinov, Mikhail S.
experimental part, p. 255 - 258 (2011/02/25)
Lysyl oxidase (LOX) is implicated in several extracellular matrix related disorders, including fibrosis and cancer. Methods of inhibition of LOX in vivo include antibodies, copper sequestration and toxic small molecules such as β-aminopropionitrile. Here,
Reversible protection of lysine to facilitate the purification of protected peptide segments
Rizo, Josep,Albericio, Fernando,Giralt, Ernest,Pedroso, Enrique
, p. 397 - 400 (2007/10/02)
The polarity of temporarily free lysine side chains can be exploited to aid in the purification of protected peptides. The amine groups can easily be reprotected after the purification step. Impurities in commercial TFE1 can cause trifluoroacetylation of free primary amines.
