172348-75-3

Basic information

• Product Name: Carbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochloride
• CAS NO: 172348-75-3
• Molecular Formula: C16H17N3O2.2ClH
• Molecular Weight: 356.252
• Mol File: 172348-75-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochloride(172348-75-3)
• EPA Substance Registry System: Carbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochloride(172348-75-3)

Safety Data

• Hazardous Substances Data: 172348-75-3(Hazardous Substances Data)

Upstream product

• 510772-07-3 4-di-tert-butoxycarbonylaminomethyl-N-hydroxy-benzamidine 
• 217313-79-6 4-(aminomethyl)benzene-1-carboximidamide dihydrochloride 
• 172348-74-2 tert-butyl ((tert-butoxycarbonyl)(4-cyanobenzyl)amino)-methanoate 
• 217313-81-0 4-(tert-Butoxycarbonylamino-methyl)-thiobenzimidic acid methyl ester 
• 217313-80-9 (4-thiocarbamoyl-benzyl)-carbamic acid tert-butyl ester 
• 162696-15-3 N-Boc-4-aminomethyl benzamidine 
• 162698-08-0 4-amidinobenzyl azide 
• 17201-43-3 4-cyanobenzyl bromide 
• 66389-80-8 tert-butyl N-[(4-cyanophenyl)methyl]carbamate 
• 217313-86-5 tert-butyl((4-((((benzyloxy)carbonyl)amino)(imino)methyl) benzyl)(tert-butoxycarbonyl)amino)methanoate 
• 162696-14-2 benzyl ((4-(((tert-butoxycarbonyl)amino)methyl)phenyl)(imino)methyl)carbamate 

Downstream Products

• 162694-63-5 melagatran 

Relevant articles and documents

Large scale preparation of protected 4-aminomethylbenzamidine. Application to the synthesis of the thrombin inhibitor, melagatran

To allow the preparation of melagatran on a multigram scale, we have investigated several approaches for the synthesis of the key intermediate 4- aminomethylbenzamidine. The only industrially suitable pathway relies on the preparation of an N-hydroxyimino