217313-80-9

Basic information

• Product Name: Carbamic acid, [[4-(aminothioxomethyl)phenyl]methyl]-, 1,1-dimethylethyl ester
• CAS NO: 217313-80-9
• Molecular Formula: C13H18N2O2S
• Molecular Weight: 266.364
• Mol File: 217313-80-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[4-(aminothioxomethyl)phenyl]methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[4-(aminothioxomethyl)phenyl]methyl]-, 1,1-dimethylethyl ester(217313-80-9)
• EPA Substance Registry System: Carbamic acid, [[4-(aminothioxomethyl)phenyl]methyl]-, 1,1-dimethylethyl ester(217313-80-9)

Safety Data

• Hazardous Substances Data: 217313-80-9(Hazardous Substances Data)

Upstream product

• 172348-74-2 tert-butyl ((tert-butoxycarbonyl)(4-cyanobenzyl)amino)-methanoate 
• 17201-43-3 4-cyanobenzyl bromide 
• 51779-32-9 iminodicarboxylic acid di-tert-butyl ester 
• 66389-80-8 tert-butyl N-[(4-cyanophenyl)methyl]carbamate 

Downstream Products

• 172348-75-3 [(4-aminomethyl-phenyl)-imino-methyl]-carbamic acid benzyl ester dihydrochloride 
• 162694-63-5 melagatran 
• 162696-14-2 benzyl ((4-(((tert-butoxycarbonyl)amino)methyl)phenyl)(imino)methyl)carbamate 
• 162696-15-3 N-Boc-4-aminomethyl benzamidine 
• 217313-81-0 4-(tert-Butoxycarbonylamino-methyl)-thiobenzimidic acid methyl ester 

Relevant articles and documents

Large scale preparation of protected 4-aminomethylbenzamidine. Application to the synthesis of the thrombin inhibitor, melagatran

To allow the preparation of melagatran on a multigram scale, we have investigated several approaches for the synthesis of the key intermediate 4- aminomethylbenzamidine. The only industrially suitable pathway relies on the preparation of an N-hydroxyimino