1779-81-3 Usage
Description
2-Amino-2-thiazoline, also known as 4,5-dihydro-1,3-thiazole, is a chemical compound characterized by the presence of an amino group at the 2nd position. It is a 1,3-thiazole derivative with a unique structure that exhibits a white to light yellow crystalline powder appearance. 2-Amino-2-thiazoline has garnered interest due to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-Amino-2-thiazoline is used as a radiation protectant for its ability to shield biological systems from the harmful effects of radiation. This application is particularly relevant in the pharmaceutical industry, where it can be utilized to protect patients undergoing radiation therapy or to safeguard medical professionals working with radioactive materials.
Used in Chemical Industry:
In the chemical industry, 2-Amino-2-thiazoline can be employed as an intermediate in the synthesis of various compounds, taking advantage of its unique chemical properties. Its versatility as a building block can lead to the development of new materials and products with specific applications in different sectors.
Used in Research and Development:
2-Amino-2-thiazoline's unique structure and properties make it an interesting candidate for research and development purposes. Scientists and researchers can explore its potential in various fields, such as drug discovery, material science, and chemical engineering, to create innovative solutions and advancements.
Synthesis Reference(s)
Journal of the American Chemical Society, 79, p. 5667, 1957 DOI: 10.1021/ja01578a022
Check Digit Verification of cas no
The CAS Registry Mumber 1779-81-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,7 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1779-81:
(6*1)+(5*7)+(4*7)+(3*9)+(2*8)+(1*1)=113
113 % 10 = 3
So 1779-81-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H6N2S.H2O4S/c4-3-5-1-2-6-3;1-5(2,3)4/h1-2H2,(H2,4,5);(H2,1,2,3,4)/p-2
1779-81-3Relevant articles and documents
-
Klayman,D.L.,McIntyre,P.T.
, p. 884 - 887 (1968)
-
Easy access to thiazolines and thiazines via tandem S-alkylation- cyclodeamination of thioamides/haloamines
Pathak, Uma,Bhattacharyya, Shubhankar,Dhruwansh, Vishwanath,Pandey, Lokesh Kumar,Tank, Rekha,Suryanarayana, Malladi V. S.
supporting information; experimental part, p. 1648 - 1651 (2011/08/10)
This is the first report of a facile synthesis of thiazolines and thiazines from a self-catalyzed, water assisted tandem S-alkylation-cyclodeamination reaction of thioamides/haloamines. The reaction is clean and efficient with simple product work-up, and is applicable to a variety of substrates.
Solvolysis of 2-amino-2-thiazoline derivatives by aliphatic amino alcohols
Mandrugin,Fedoseev,Dubovaya,Rodyunin,Semenko
, p. 1382 - 1388 (2007/10/03)
The opening of the thiazoline ring upon the action of amino alcohols was studied. The effects of the reagent ratio and structures of the heterocycles and amino alcohols on aminolysis were investigated. A new method was developed for the preparative synthesis of a series of N′-(hydroxyalkyl)-2-guanidinoalkanethiols.
