18023-52-4

Basic information

• Product Name: 1-Methylheptyl(trimethylsilyl) ether
• Synonyms: (1-Methylheptyloxy)trimethylsilane;1-Methylheptyl(trimethylsilyl) ether;2-(Trimethylsiloxy)octane;2-Trimethylsiloxyoctane
• CAS NO: 18023-52-4
• Molecular Formula: C₁₁H₂₆OSi
• Molecular Weight: 0
• Mol File: 18023-52-4.mol
• Article Data: 42

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methylheptyl(trimethylsilyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methylheptyl(trimethylsilyl) ether(18023-52-4)
• EPA Substance Registry System: 1-Methylheptyl(trimethylsilyl) ether(18023-52-4)

Safety Data

• Hazardous Substances Data: 18023-52-4(Hazardous Substances Data)

Usage

Class

Ethers

Structure

Contains an oxygen atom bonded to two alkyl groups, specifically a 1-methylheptyl group and a trimethylsilyl group

1-Methylheptyl group

A seven-carbon chain with a methyl branch

Trimethylsilyl group

Three methyl groups bonded to a silicon atom

Use

Commonly used as a protecting group in organic synthesis to temporarily mask reactive functional groups, such as alcohols and carboxylic acids, during chemical reactions

Selectivity

Ability to selectively and reversibly block specific functional groups

Value

Valuable tool in the synthesis of complex organic molecules due to its selectivity and reversibility.

Upstream product

• 4128-31-8 rac-octan-2-ol 
• 107-46-0 Hexamethyldisiloxane 
• 1541-09-9 methyl 2-octyl ether 
• 16029-98-4 trimethylsilyl iodide 
• 75-77-4 chloro-trimethyl-silane 
• 111-13-7 hexyl-methyl-ketone 
• 762-72-1 allyl-trimethyl-silane 
• 66448-28-0 5,5-dimethyl-1,3-bis(TMS)hydantoin 
• 920-68-3 heptamethyldisilazane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 33861-17-5 phenyl trimethylsilyl selenide 
• 3768-55-6 N-trimethylsilylaniline 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 36049-78-2 2-iodooctane 
• 407-95-4 2-fluorooctane 
• 111-67-1 2-octene 
• 111-66-0 oct-1-ene 
• 4128-31-8 rac-octan-2-ol 
• 111-13-7 hexyl-methyl-ketone 
• 67810-87-1 2-Octyl benzyl ether 
• 2074-06-8 2-octanone 2,4-dinitrophenylhydrazone 
• 74112-36-0 2-Octyl acetate 
• 2216-41-3 formic acid 1-methyl-heptyl ester 
• 6938-51-8 2-octyl benzoate 
• 2570-96-9 2-octyl cyanide 
• 99064-98-9 2-isocyanatooctane 
• 628-61-5 2-chlorooctane 

Relevant articles and documents

Mild, Effective and Selective Method for the Silylation of Alcohols Using Silazanes Promoted by Catalytic Tetrabutylammonium Fluoride

The presence of catalytic amounts (ca. 0.02 equiv.) of tetrabutylammonium fluoride (TBAF) significantly promoted the silylation of alcohols using a variety of available silazanes under mild conditions with high chemoselectivity, wherein the choice of sila

Room temperature silylation of alcohols catalyzed by metal organic frameworks

The commercial Al(OH)(BDC) (BDC: 1,4-benzenedicarboxylic acid) metal organic framework (Basolite A100) is a suitable heterogeneous catalyst for the silylation of benzylic and aliphatic alcohols by hexamethyldisilazane in toluene at room temperature. Al(OH

Highly efficient protection of alcohols and phenols catalysed by tin porphyrin supported on MIL-101

The catalytic activity of 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatotin(IV) trifluoromethanesulfonate, [SnIV(TNH2PP)(OTf)2], supported on chloromethylated MIL-101, was investigated in the trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) and also their tetrahydropyranylation with 3,4-dihydro-2H-pyran. Excellent yields, mild reaction conditions, short reaction times and reusability of the catalyst without significant decrease in its initial activity are noteworthy advantages of this supported catalyst.