184165-64-8

Basic information

• Product Name: 1-(4-bromophenyl)-3-buten-1-one
• Synonyms: 1-(4-bromophenyl)-3-buten-1-one
• CAS NO: 184165-64-8
• Molecular Weight: 225.085
• Mol File: 184165-64-8.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 1-(4-bromophenyl)-3-buten-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-3-buten-1-one(184165-64-8)
• EPA Substance Registry System: 1-(4-bromophenyl)-3-buten-1-one(184165-64-8)

Safety Data

• Hazardous Substances Data: 184165-64-8(Hazardous Substances Data)

Upstream product

• 106650-98-0 1-(4-bromophenyl)but-3-en-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 
• 873-75-6 4-bromobenzenemethanol 
• 623-00-7 4-bromobenzenecarbonitrile 
• 334927-92-3 methyl 2-(4'-bromophenyl)-2-hydroxy-4-pentenoate 
• 127709-20-0 α-hydroxy-(p-bromophenyl)-acetic acid methyl ester 
• 6048-21-1 4-bromobenzoyl cyanide 
• 106-95-6 allyl bromide 
• 334928-06-2 2-(4'-bromophenyl)-2-hydroxy-4-pentenoic acid 
• 2622-05-1 allylmagnesium bromide 
• 192436-83-2 4-bromo-N-methoxy-N-methylbenzamide 
• 754-56-3 3-(tert-butyl)-2,2-dimethylhex-5-en-3-ol 
• 586-75-4 4-chlorobenzoyl chloride 

Downstream Products

• 1612790-51-8 C₁₆H₁₂BrN₃O 
• 1616603-25-8 C₁₂H₁₂BrNO₂ 
• 4995-11-3 2-(4-bromophenyl)-1H-pyrrole 
• 21262-87-3 3-(4-bromophenyl)-5-methyl-1,2-oxazole 
• 557085-43-5 (E)-1-(4-bromophenyl)-4-hydroxy-2-buten-1-one 
• 203634-91-7 4,5-dihydro[3-(4-bromophenyl)-5-(hydroxymethyl)]isoxazole 

Relevant articles and documents

Visible Light-Promoted Recyclable Carbon Nitride-Catalyzed Dioxygenation of β,γ-Unsaturated Oximes

A visible-light-induced dioxygenation of β,γ-unsaturated oximes for the synthesis of diverse useful isoxazolines bearing a hydroxyl moiety was developed by employing graphitic carbon nitride (g-C3N4) as a heterogeneous photocatalyst under an air atmosphere. Noted that, the eminent advantages of this metal-free protocol include step economy, easy operation, a recyclable photocatalyst, external reductant-/oxidant-free and mild reaction conditions. Additionally, mechanistic studies indicated hydroxyl radical was generated under the photocatalysis of g-C3N4.

Copper-catalyzed radical oxyallylation of olefins for the construction of alkene-containing isoxazolines

A radical-mediated approach to alkene oxyallylation using allylic oximes is described. The reaction proceeds under copper-catalytic redox-neutral conditions and tolerates various functional groups. This protocol thus enables the synthesis of structurally valuable isoxazolines and the introduction of a versatile olefin motif in a single step.

Copper-Catalyzed Aerobic Cyclization of β,γ-Unsaturated Hydrazones with Concomitant CC Bond Cleavage

A Cu-catalyzed aerobic oxidative cyclization of β,γ-unsaturated hydrazones for the preparation of pyrazole derivatives has been developed. The hydrazonyl radical promoted the cyclization, along with a concomitant CC bond cleavage of β,γ-unsaturated hydrazones. This process has been verified via several control experiments, including a radical-trapping study, an 18O-labeling method, and the identification of the possible byproducts. The advantages of this reaction include operational simplicity, a broad reaction scope, and a mild selective reaction process.