184916-28-7Relevant articles and documents
Synthesis of a novel amino acid based dendrimer
Mulders, Suzanne J.E.,Brouwer, Arwin J.,Van Der Meer, Peter G.J.,Liskamp, Rob M.J.
, p. 631 - 634 (1997)
An easy accessible dendrimer monomer 3,5-bis(2-tert-butyloxycarbonyl aminoethoxy) benzoic acid methyl ester 1 was designed. The monomer was converted to both the 'surface' and 'braching' monomer in a versatile synthesis of a novel amino acid based dendrimer by the covergent method, using the well established and high-yielding BOP-peptide coupling method.
Tetramaleimide connexin and application thereof
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Paragraph 0371; 0372; 0373; 0374, (2018/03/26)
The invention relates to tetramaleimide connexin and application thereof. Particularly, the invention relates to a compound shown as a formula I and application of the compound serving as connexin inpreparing antibody drug conjugate. The antibody drug con
OPTICAL IMAGING PROBES
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Paragraph 0087; 0092; 0093, (2014/05/20)
The present invention relates to methods of visualising cells especially although not exclusively in vivo using a dye, such as a dendrimer-dye molecule or polybranched-dye molecule which is internalised by the cells and thus permits subsequent visualisation by confocal fluorescence endomicroscopy or other optical detectors. There is also provided internally quenched probes for use in visualising cells especially although not exclusively in vivo by confocal fluorescence endomicroscopy and the use of internally quenched probes in combination with confocal fluorescence endomicroscopy, for visualising cells by virtue of internalisation and dequenching of a probe by the cells. In a particular embodiment the cells are activated neutrophils, such as within the lung of a subject.