352426-84-7Relevant articles and documents
Convergent synthesis and diversity of amino acid based dendrimers
Brouwer, Arwin J.,Mulders, Suzanne J. E.,Liskamp, Rob M. J.
, p. 1903 - 1915 (2007/10/03)
The synthesis of amino acid based dendrimers 25 (fifth generation, 32 endgroups), 30 (fourth generation, 81 endgroups), chiral dendrimer 23 (third generation, 8 endgroups) as well as core-modified dendrimers 34 and 38 by the convergent method is described. The amino acid building blocks are derived from hydroxybenzoic acid derivatives and amino alcohol derivatives, and access to a considerable molecular diversity of these novel dendrimers can be achieved, The synthesis can be carried out on a relatively large scale, and this easy access of the dendrimers may lead to many potential applications.
Synthesis of a novel amino acid based dendrimer
Mulders, Suzanne J.E.,Brouwer, Arwin J.,Van Der Meer, Peter G.J.,Liskamp, Rob M.J.
, p. 631 - 634 (2007/10/03)
An easy accessible dendrimer monomer 3,5-bis(2-tert-butyloxycarbonyl aminoethoxy) benzoic acid methyl ester 1 was designed. The monomer was converted to both the 'surface' and 'braching' monomer in a versatile synthesis of a novel amino acid based dendrimer by the covergent method, using the well established and high-yielding BOP-peptide coupling method.