187960-76-5

Basic information

• Product Name: 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester
• Synonyms: 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester
• CAS NO: 187960-76-5
• Molecular Weight: 1099.24
• Mol File: 187960-76-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester(187960-76-5)
• EPA Substance Registry System: 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester(187960-76-5)

Safety Data

• Hazardous Substances Data: 187960-76-5(Hazardous Substances Data)

Upstream product

• 184916-28-7 3,5-bis-(2-tert-butyloxycarbonylamino-ethoxy) methyl benzoate 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 187960-74-3 3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid 
• 39684-80-5 2-(tert-butoxycarbonylamino)ethyl bromide 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 405298-02-4 3,5-bis-{2-[3,5-bis-(2-amino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester 
• 352426-84-7 3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid 

Relevant articles and documents

Convergent synthesis and diversity of amino acid based dendrimers

The synthesis of amino acid based dendrimers 25 (fifth generation, 32 endgroups), 30 (fourth generation, 81 endgroups), chiral dendrimer 23 (third generation, 8 endgroups) as well as core-modified dendrimers 34 and 38 by the convergent method is described. The amino acid building blocks are derived from hydroxybenzoic acid derivatives and amino alcohol derivatives, and access to a considerable molecular diversity of these novel dendrimers can be achieved, The synthesis can be carried out on a relatively large scale, and this easy access of the dendrimers may lead to many potential applications.

Synthesis of a novel amino acid based dendrimer

An easy accessible dendrimer monomer 3,5-bis(2-tert-butyloxycarbonyl aminoethoxy) benzoic acid methyl ester 1 was designed. The monomer was converted to both the 'surface' and 'braching' monomer in a versatile synthesis of a novel amino acid based dendrimer by the covergent method, using the well established and high-yielding BOP-peptide coupling method.