185627-00-3Relevant articles and documents
4-(tert-Butyldimethylsilyloxy)benzylidene acetal: A novel benzylidene-type protecting group for 1,2-diols
Kaburagi, Yosuke,Osajima, Hiroyuki,Shimada, Kousei,Tokuyama, Hidetoshi,Fukuyama, Tohru
, p. 3817 - 3821 (2004)
A novel 1,2-diol-protecting group, p-silyloxybenzylidene group, has been developed. In addition to the stepwise deprotection conditions including desilylation and the subsequent acidic hydrolysis of the p-hydroxybenzylidene group in AcOH-THF-H2O, we have established the one-pot deprotection under basic conditions [K2CO3 (5equiv), NH 2OH·HCl (5equiv), and CsF (1equiv) in MeOH-H2O].
Protection of diols with 4-(tert-Butyldimethylsilyloxy)Benzylidene acetal and its deprotection: (4-((4R,5R)-4,5-diphenyl-1,3-dioxolan-2-yl)phenoxy) (tertbutyl)dimethylsilane
Osajima, Hiroyuki,Fujiwara, Hideto,Okano, Kentaro,Tokuyama, Hidetoshi,Fukuyama, Tohru,Denmark, Scott E.,Chang, Wen-Tau T.
scheme or table, p. 130 - 140 (2011/03/21)
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