190315-43-6

Basic information

• Product Name: 1,4-Dideoxy-1,4-epithio-D-ribitol
• Synonyms: 1,4-Dideoxy-1,4-epithio-D-ribitol
• CAS NO: 190315-43-6
• Molecular Weight: 0
• Mol File: 190315-43-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,4-Dideoxy-1,4-epithio-D-ribitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dideoxy-1,4-epithio-D-ribitol(190315-43-6)
• EPA Substance Registry System: 1,4-Dideoxy-1,4-epithio-D-ribitol(190315-43-6)

Safety Data

• Hazardous Substances Data: 190315-43-6(Hazardous Substances Data)

Usage

General Description

1,4-Dideoxy-1,4-epithio-D-ribitol, also known as 4'-Thio-ribose, is a synthetic chemical compound that belongs to the class of carbohydrates. It is a derivative of ribitol, which is a type of sugar alcohol, and contains a sulfur atom in the furanose ring. This chemical has been studied for its potential use in pharmaceuticals and biotechnology, particularly in the development of antiviral and antimicrobial agents. It is also being investigated for its role in the synthesis of nucleoside analogs, which are important in the field of nucleic acid chemistry. Additionally, 1,4-Dideoxy-1,4-epithio-D-ribitol has been researched for its potential applications in the field of glycochemistry, where it may be used as a building block for the synthesis of complex carbohydrates.

Upstream product

• 596103-06-9 ((3aS,4R,6aR)-2,2- dimethyltetrahydrothieno[3,4-d][1,3]dioxol-4-yl)methanol 
• 50-69-1 D-ribose 
• 152006-17-2 2,3-O-isopropylidene-L-lyxono-1,4-lactone 
• 89747-54-6 (3R,4R,5R)-4,5-dihydro-3,4-(O,O)-isopropylidene-5-mesyloxymethyl-2-(3H)-furanone 
• 30725-00-9 2,3-O-isopropylidene-D-ribonic-γ-lactone 
• 5336-08-3 D-Ribono-1,4-lactone 
• 875753-49-4 tert-butyl(((3aS,4R,6aR)-2,2-dimethyltetrahydrothieno[3,4-d][1,3]dioxol-4-yl)methoxy)dimethylsilane 
• 1044813-00-4 5-O-tert-butyldimethylsilyl-2,3-O-isopropylidene-L-lyxonic acid-1,4-lactone 
• 541546-94-5 allyl α,β-D-ribofuranoside 
• 532-20-7 D-Ribose 
• 541546-97-8 1,4-anhydro-2,3,5-tri-O-p-methoxybenzyl-4-thio-D-ribitol 
• 497847-33-3 1,4-dibromo-1,4-dideoxy-2,3,5-tri-O-benzyl-L-lyxitol 
• 291758-10-6 1,4-anhydro-2,3,5-tri-O-benzyl-4-thio-D-ribitol 
• 190315-42-5 (+)-tri-O-acetyl-1-deoxy-4-thio-D-ribose 

Downstream Products

• 596103-06-9 ((3aS,4R,6aR)-2,2- dimethyltetrahydrothieno[3,4-d][1,3]dioxol-4-yl)methanol 
• 291758-13-9 (R)-1,4-anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol 
• 291758-12-8 (6aR,9R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocin-9-yl 2,4-dimethoxybenzoate 
• 872217-40-8 2,3,5-tri-O-p-methoxybenzyl-1,4-dideoxy-1,4-[[(2S,3S)-2,4-O-benzylidene-3-(sulfooxy)butyl]-(R)-episulfoniumylidene]-D-ribitol 
• 898806-15-0 1,4-anhydro-2-deoxy-2-acetamido-3,5-di-O-benzyl-4-thio-D-arabinitol 
• 898806-16-1 1,4-anhydro-2-deoxy-2-azido-3,5-di-O-benzyl-4-thio-D-arabinitol 
• 541546-97-8 1,4-anhydro-2,3,5-tri-O-p-methoxybenzyl-4-thio-D-ribitol 

Relevant articles and documents

Synthesis of 1-Deoxy-4-thio-D-ribose starting from thiophene-2-carboxylic acid

The de novo synthesis of 1-deoxy-4-thio-D-ribose starting from thiophene-2-carboxylic acid is described, The key step is the cis-dihydroxylation of S-2-acetoxy-2,5-dihydrothiophene, which is obtained by enzymatic alcoholysis.

Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC

Stable NAD+ analogues carrying single atom substitutions in either the furanose ring or the nicotinamide part have proven their value as inhibitors for NAD+-consuming enzymes. To investigate the potential of such compounds to inhibit

An access to the β-anomer of 4′-thio-C-ribonucleosides: Hydroboration of 1-C-aryl- or 1-C-heteroaryl-4-thiofuranoid glycals and its regiochemical outcome

We have developed a novel method for the synthesis of the β-anomer of 4′-thio-C-ribonucleosides from 3,5-O-(di-tert-butylsilylene)-4- thiofuranoid glycal. Palladium-catalyzed coupling of 1-tributylstannyl-4- thiofuranoid glycal with iodobenzene or a heter

4’-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS

The present invention provides modified oligomeric compounds and compositions of oligomeric compounds for use in the RNA interference pathway of gene modulation. The modified oligomeric compounds include siRNA and asRNA having at least one affinity modification.