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194423-53-5

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194423-53-5 Usage

Description

EZETIMIBE ANALOGUE, also known as E975000 or SCH 58053, is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine. It is a white solid with chemical properties that make it a valuable compound in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
EZETIMIBE ANALOGUE is used as a cholesterol-lowering agent for the treatment of hypercholesterolemia. It works by inhibiting the absorption of cholesterol in the intestine, thereby reducing the levels of low-density lipoprotein (LDL) cholesterol in the blood. This helps in the prevention and management of cardiovascular diseases.
Used in Research and Development:
EZETIMIBE ANALOGUE is also used as a research tool in the development of new drugs targeting cholesterol metabolism and related conditions. Its potent and selective inhibition of lymphatic cholesterol transport makes it a valuable compound for studying the underlying mechanisms of cholesterol absorption and transport in the body.
Used in Drug Delivery Systems:
Similar to gallotannin, EZETIMIBE ANALOGUE can be incorporated into novel drug delivery systems to enhance its applications and efficacy. These systems can improve the delivery, bioavailability, and therapeutic outcomes of the compound, making it more effective in treating hypercholesterolemia and related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 194423-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,4,2 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 194423-53:
(8*1)+(7*9)+(6*4)+(5*4)+(4*2)+(3*3)+(2*5)+(1*3)=145
145 % 10 = 5
So 194423-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C26H23ClFNO3/c27-19-5-3-18(4-6-19)26(32)15-13-25(14-16-26)23(17-1-11-22(30)12-2-17)29(24(25)31)21-9-7-20(28)8-10-21/h1-12,23,30,32H,13-16H2/t23?,25-,26+

194423-53-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R)-7-(4-chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-1-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-3-one

1.2 Other means of identification

Product number -
Other names (3R,4|A,7|A)-7-(4-Chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:194423-53-5 SDS

194423-53-5Downstream Products

194423-53-5Relevant articles and documents

A Catalytic Asymmetric Synthesis of a Spirofused Azetidinone as a Cholesterol Absorption Inhibitor

Wu, Guangzhong,Tormos, Wanda

, p. 6412 - 6414 (1997)

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