201038-72-4

Basic information

• Product Name: (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
• Synonyms: (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
• CAS NO: 201038-72-4
• Molecular Weight: 442.623
• Mol File: 201038-72-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine(201038-72-4)
• EPA Substance Registry System: (R)-1-(2-(1-(3-benzyloxy-benzenesuylfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine(201038-72-4)

Safety Data

• Hazardous Substances Data: 201038-72-4(Hazardous Substances Data)

Upstream product

• 132482-05-4 methyl (R)-2-[N(1')-(tert-butoxycarbonyl)pyrrolidin-2'-yl]ethanoate 
• 152665-79-7 (R)-tert-butyl 2-(2-diazoacetyl)pyrrolidine-1-carboxylate 
• 132482-06-5 tert-butyl (2R)-2-(2-hydroxyethyl)pyrrolidine-1-carboxylate 
• 344-25-2 D-Prolin 
• 37784-17-1 N-(tert-butoxycarbonyl)-D-proline 
• 100-39-0 benzyl bromide 
• 591-20-8 3-Bromophenol 
• 132482-08-7 (R)-N-Boc-2-(2-(methylsulphonyloxy)ethyl)pyrrolidine 
• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 132482-10-1 (R)-1-<(1,1-dimethylethoxy)carbonyl>-2-pyrrolidinemethanolmethanesulfonate 
• 59378-81-3 1-(tert-butoxycarbonyl)prolin-2R-ol 
• 626-58-4 4-methylpiperidin 
• 162711-45-7 3-benzyloxybenzenesulfonyl chloride 
• 201039-15-8 (R)-2-[2-(4-methyl-piperidin-1-yl)ethyl]pyrrolidine 

Downstream Products

• 261901-57-9 SB 269970 A 
• 261901-57-9 (R)-3-(2-(2-(4-methyl-piperidin-1-yl)ethyl)-pyrrolidine-1-sulfonyl)-phenol hydrochloride 

Relevant articles and documents

Efficient Arndt-Eistert synthesis of selective 5-HT7 receptor antagonist SB-269970

This contribution describes a novel Arndt-Eistert approach for the efficient synthesis of the potent and selective 5-HT7-antagonist, (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970), from D-proline. The synthesis was ca