208345-54-4Relevant articles and documents
General Enantioselective C?H Activation with Efficiently Tunable Cyclopentadienyl Ligands
Jia, Zhi-Jun,Merten, Christian,Gontla, Rajesh,Daniliuc, Constantin G.,Antonchick, Andrey P.,Waldmann, Herbert
supporting information, p. 2429 - 2434 (2017/02/23)
Cyclopentadienyl (Cp) ligands enable efficient steering of various transition-metal-catalyzed transformations, in particular enantioselective C?H activation. Currently only few chiral Cp ligands are available. Therefore, a conceptually general approach to
Sulfinimine mediated asymmetric synthesis of 3-substituted-1(2H)- isoquinolones: (3R,4S)-(-)-4-hydroxy-3-phenyltetrahydroisoquinoline
Davis, Franklin A.,Andemichael, Yemane W.
, p. 3099 - 3102 (2007/10/03)
A general approach to enantiomerically pure 3-substituted-1(2H)- isoquinolones is illustrated by the addition of lateral lithiated amide 7 to sulfinimine 5. Isoquinolone 8 is readily transformed into (3R,4S)-(-)-4- hydroxy-3-phenyltetrahydroisoquinoline 15 via hydroxylation and reduction.