2129-52-4

Basic information

• Product Name: 2-(4,5-dimethoxy-2-nitrophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
• CAS NO: 2129-52-4
• Molecular Formula: C₂₀H₂₄N₂O₇
• Molecular Weight: 404.4138
• Mol File: 2129-52-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 632.8°C at 760 mmHg
• Flash Point: 336.5°C
• Density: 1.226g/cm³
• Vapor Pressure: 6.39E-16mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 2-(4,5-dimethoxy-2-nitrophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4,5-dimethoxy-2-nitrophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(2129-52-4)
• EPA Substance Registry System: 2-(4,5-dimethoxy-2-nitrophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide(2129-52-4)

Safety Data

• Hazardous Substances Data: 2129-52-4(Hazardous Substances Data)

Usage

Molecular structure

The compound has a complex molecular structure with a nitro group, two methoxy groups, and an amide functional group.

Therapeutic potential

It is commonly used in research and pharmaceuticals due to its potential therapeutic properties.

Analgesic and anti-inflammatory effects

The molecular structure suggests that the compound may have analgesic and anti-inflammatory effects, making it a promising candidate for the development of new medications.

Interactions with biological molecules

The presence of aromatic rings and an amide group in the compound indicates that it may have interactions with other biological molecules, such as receptors or enzymes, making it an interesting target for further study in drug development.

Upstream product

• 73357-18-3 (4,5-dimethoxy-2-nitrophenyl)acetic acid 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 53602-52-1 4,5-dimethoxy-2-nitrophenylacetic acid chloride 
• 4230-93-7 3,4-dimethoxynitrostyrene 

Downstream Products

• 16251-41-5 1-(2'-nitro-4',5'-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline 
• 77513-48-5 1-(4',5'-dimethoxy-2'-nitro-α-oxobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline 
• 20323-72-2 (6,7-dimethoxyisoquinolin-1-yl)(4,5-dimethoxy-2-nitrophenyl)-methanone 
• 5574-24-3 oxoglaucine 

Relevant articles and documents

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.

The SYNTHESIS OF ERYTHRO- AND THREO-N-METHYL 7-HYDROXY-1,2,9,10-TETRAMETHOXYAPORPHINE

The total synthesis of the title compounds is described.