21481-86-7

Basic information

• Product Name: (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol
• CAS NO: 21481-86-7
• Molecular Weight: 190.285
• Mol File: 21481-86-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol(21481-86-7)
• EPA Substance Registry System: (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol(21481-86-7)

Safety Data

• Hazardous Substances Data: 21481-86-7(Hazardous Substances Data)

Upstream product

• 63882-42-8 2-(2-methylphenyl)cyclohexanone 
• 523-25-1 (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol 
• 523-25-1 (+/-)-cis-2-(o-Tolyl)-cyclohexanol <(+/-)-1(a)-Hydroxy-2(e)-o-tolyl-cyclohexan> 
• 932-31-0 ortho-tolylmagnesium bromide 
• 286-20-4 cyclohexane-1,2-epoxide 
• 95-46-5 2-methylphenyl bromide 

Downstream Products

• 157604-32-5 (1R,2S)-trans-2-(2-methylphenyl)-1-cyclohexanol 
• 18180-77-3 (1S,2R)-trans-2-(2-methylphenyl)-1-cyclohexanol 
• 523-25-1 (+/-)-cis-2-(o-Tolyl)-cyclohexanol <(+/-)-1(a)-Hydroxy-2(e)-o-tolyl-cyclohexan> 
• 63882-42-8 2-(2-methylphenyl)cyclohexanone 

Relevant articles and documents

Palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones for the synthesis oftranscycloalkanols through dynamic kinetic resolution under acidic conditions

The first efficient palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones has been described through dynamic kinetic resolution under acidic conditions, providing a facile access to chiraltranscycloalkanol derivatives with excellent enantioselectivities.

Copper(II)-catalyzed meta-selective direct arylation of α-aryl carbonyl compounds

Strong competition: A method for the meta-selective arylation of the highly versatile α-aryl carbonyl motif using diaryliodonium salts is described. In this CuII-catalyzed process the remote carbonyl group is capable of overpowering even strongly para-directing functionalities to form the elusive meta-products (see scheme). Remarkably, the arylation process can also operate under metal-free conditions.

Enzymatic resolution of trans-2-arylcyclohexan-1-ols using crude chicken liver esterase (CCLE) as biocatalyst

Homochiral trans-2-arylcyclohexan-1-ols were synthesized via crude chicken liver esterase (CCLE) mediated enantioselective hydrolysis of the corresponding racemic acetates.