523-25-1

Basic information

• Product Name: 2-(2-methylphenyl)cyclohexan-1-ol
• Synonyms: 2-(2-methylphenyl)cyclohexan-1-ol
• CAS NO: 523-25-1
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 523-25-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 316.4°Cat760mmHg
• Flash Point: 123°C
• Appearance: /
• Density: 1.034g/cm³
• Vapor Pressure: 0.000173mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 2-(2-methylphenyl)cyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methylphenyl)cyclohexan-1-ol(523-25-1)
• EPA Substance Registry System: 2-(2-methylphenyl)cyclohexan-1-ol(523-25-1)

Safety Data

• Hazardous Substances Data: 523-25-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Sweet, floral

Usage

Production of perfumes and fragrances

Potential applications

Intermediate for the synthesis of pharmaceuticals and other organic compounds

Safety precautions

May be harmful if ingested or inhaled, can cause irritation to the eyes and skin

InChI:InChI=1/C13H18O/c1-10-6-2-3-7-11(10)12-8-4-5-9-13(12)14/h2-3,6-7,12-14H,4-5,8-9H2,1H3

Upstream product

• 932-31-0 ortho-tolylmagnesium bromide 
• 286-20-4 cyclohexane-1,2-epoxide 
• 95-46-5 2-methylphenyl bromide 
• 63882-42-8 2-(2-methylphenyl)cyclohexanone 
• 930-68-7 cyclohexenone 
• 523-25-1 (+/-)-trans-2-(2-methylphenyl)cyclohexan-1-ol 

Downstream Products

• 157604-32-5 (1R,2S)-trans-2-(2-methylphenyl)-1-cyclohexanol 
• 63882-42-8 2-(2-methylphenyl)cyclohexanone 
• 21481-86-7 (-)-cis-2-(o-Tolyl)-cyclohexanol <(-)-1(a)-Hydroxy-2(e)-o-tolyl-cyclohexan> 
• 18180-77-3 (1S,2R)-trans-2-(2-methylphenyl)-1-cyclohexanol 
• 523-25-1 (+/-)-cis-2-(o-Tolyl)-cyclohexanol <(+/-)-1(a)-Hydroxy-2(e)-o-tolyl-cyclohexan> 
• 1309458-22-7 1-(cyclohexa-2,4-dienyl)-2-methylbenzene 
• 1309458-29-4 trimethyl(6-o-tolylcyclohex-1-enyloxy)silane 

Relevant articles and documents

ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS

Provided herein are arylcyclohexylamine derivatives and their use in the treatment of psychiatric disorders.

Aromatic compound, preparation method and use of aromatic compound

The invention relates to an aromatic compound, a preparation method and use of the aromatic compound, andspecifically discloses a compound represented by the following formula (I), or a tautomer or anenantiomer or a diastereomer or a racemate of the compound or a mixture of the compound or a pharmaceutically acceptable salt of the compound. The invention further discloses a preparation method ofthe compound and application of the compound in treating nervous systemdiseases.

Construction of a chiral quaternary carbon center by catalytic asymmetric alkylation of 2-arylcyclohexanones under phase-transfer conditions

In this paper, we present an asymmetric alkylation of modified 2-arylcyclohexanones that employs a novel chiral ammonium bromide as a phase-transfer catalyst and an achiral auxiliary as a controller to improve the enantioselectivity to afford optically enriched products having a chiral quaternary carbon center.