221272-69-1

Basic information

• Product Name: 1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(2-chloro-vinyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione
• CAS NO: 221272-69-1
• Molecular Weight: 655.382
• Mol File: 221272-69-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(2-chloro-vinyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(2-chloro-vinyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(221272-69-1)
• EPA Substance Registry System: 1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(2-chloro-vinyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(221272-69-1)

Safety Data

• Hazardous Substances Data: 221272-69-1(Hazardous Substances Data)

Upstream product

• 162052-68-8 3'-O-tert-Butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-formyl-thymidin 
• 29949-92-6 (chloromethylene)triphenylphosphorane 

Relevant articles and documents

Nucleosides and nucleotides. 183. Synthesis of 4'α-branched thymidines as a new type of antiviral agent

A series of 4'αr-branched thymidines was synthesized and evaluated as potential antiviral agents. 4'-Ethylthymidine (3), 4'-ethenylthymidine (5), and 4'-ethynylthymidine (6) exhibited potent anti-HSV-1 and anti-HIV-1 activities with no significant cytotoxicity.