221293-02-3

Basic information

• Product Name: (R)-4-benzyl-3-((R)-4-methylhexanoyl)oxazolidin-2-one
• Synonyms: (R)-4-benzyl-3-((R)-4-methylhexanoyl)oxazolidin-2-one
• CAS NO: 221293-02-3
• Molecular Weight: 289.375
• Mol File: 221293-02-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-4-benzyl-3-((R)-4-methylhexanoyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-benzyl-3-((R)-4-methylhexanoyl)oxazolidin-2-one(221293-02-3)
• EPA Substance Registry System: (R)-4-benzyl-3-((R)-4-methylhexanoyl)oxazolidin-2-one(221293-02-3)

Safety Data

• Hazardous Substances Data: 221293-02-3(Hazardous Substances Data)

Upstream product

• 52745-93-4 (4R)-4-methylhexanoic acid 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 53353-03-0 (R)-(-)-2,6-dimethyl-2-octene 
• 313653-16-6 methanesulfonic Acid (S)-3,7-dimethyl-oct-6-enyl Ester 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 70432-01-8 (R)-4-methyl-hexanoyl chloride 
• 372504-89-7 (R)-4-benzyl-2-oxazolidinone lithium salt 

Downstream Products

• 446262-64-2 (4R)-4-benzyl-3-[(2S,4R)-2,4-dimethylhexanoyl]-1,3-oxazolidin-2-one 
• 221293-18-1 2-((1R,3R)-1-tert-Butoxycarbonylamino-3-methyl-pentyl)-5-(1H-indol-3-yl)-oxazole-4-carboxylic acid benzyl ester 
• 221293-19-2 2-((1R,3R)-1-Amino-3-methyl-pentyl)-5-(1H-indol-3-yl)-oxazole-4-carboxylic acid benzyl ester 
• 221293-03-4 (R)-3-((2R,4R)-2-Azido-4-methyl-hexanoyl)-4-benzyl-oxazolidin-2-one 

Relevant articles and documents

Synthesis of the Entomopathogenic Fungus Metabolites Militarinone C and Fumosorinone A

Militarinone C and fumosorinone A, 3-oligoenoyltetramic acids produced by insect pathogenic fungi, were synthesized for the first time. The pyrrolidine-2,4-dione ring was closed through a late-stage Dieckmann condensation of N-(β-ketoacyl) derivatives of tyrosine, obtained by its acylation with either thioesters or Meldrum's acid derivatives bearing the all-trans-polyene side chain. The latter was built up from (S)-citronellol via an Evans methylation and Wittig or HWE olefinations.

First total synthesis of martefragin A, a potent inhibitor of lipid peroxidation isolated from sea alga

The first total synthesis of martefragin A, a potent inhibitor of lipid peroxidation isolated from sea alga, has been accomplished and the absolute configurations of two stereogenic centers were determined. Synthetic martefragin A, its stereo isomers, and some analogs showed strong inhibitory activity against lipid peroxidation rat liver microsome.