22145-26-2Relevant articles and documents
Synthesis and in vitro evaluation of 2-[11C]methoxyestradiol-3, 17β-O,O-bissulfamate for in vivo studies of angiogenesis
Kang, Choong Mo,Choe, Yearn Seong,Jung, Kyung-Ho,Choi, Joon Young,Lee, Kyung-Han,Kim, Byung-Tae
, p. 783 - 787 (2012/05/20)
In the present study, 2-methoxyestradiol-3,17β-O,O-bissulfamate (1), a known angiogenesis inhibitor, was prepared in a radiolabeled form by 11C-methylation of 2-hydroxyestradiol-3,17β-O,O-bis(N-trityl) sulfamate (6) followed by detritylation. S
Glycosides of catechol estrogens
-
, (2008/06/13)
There are described novel glycosides of catechol estrogen, a method of preparing the same, and a medicament comprising one of the glycosides as an active ingredient. The glycosides are shown by the formula of STR1 wherein X is carbonyl group or STR2 R10 is hydroxyl group or glycosyloxy group, and R2 is a hydrogen atom or ethynyl group; R11 is a hydrogen atom, hydroxyl group, or glycosyloxy group; R12 is hydroxyl group or glycosyloxy group; and R13 is hydroxyl group or glycosyloxy group, in which glycosyloxy group is selected from the group consisting of glucosyloxy, galactosyloxy, mannosyloxy, arabinosyloxy, ribosyloxy, xylosyloxy, fructosyloxy, rhamnosyloxy, fucosyloxy, maltosyloxy, cellobiosyloxy, lactosyloxy, sucrosyloxy, maltotriosyloxy, maltotetraosyloxy, maltopentaosyloxy, maltohexaosyloxy, maltoheptaosyloxy, and sialosyloxy, and in this case, at least one of R10, R11, R12, and R13 is glycosyloxy group as defined above.