223674-20-2

Basic information

• Product Name: N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzamide
• Synonyms: N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzamide
• CAS NO: 223674-20-2
• Molecular Weight: 353.375
• Mol File: 223674-20-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzamide(223674-20-2)
• EPA Substance Registry System: N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzamide(223674-20-2)

Safety Data

• Hazardous Substances Data: 223674-20-2(Hazardous Substances Data)

Upstream product

• 550358-40-2 benzyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]carbamate 
• 550358-42-4 ethyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-(2,2-dichlorovinyl)-5,6-dimethoxybenzimidate 
• 550358-41-3 N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-(2,2-dichlorovinyl)-5,6-dimethoxybenzamide 
• 550358-44-6 ethyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]-2-ethynyl-5,6-dimethoxybenzimidate 
• 171779-77-4 2-(2,2-dichlorovinyl)-5,6-dimethoxybenzoic acid 
• 1484-85-1 3,4-methylenedioxyphenylethylamine 
• 82735-27-1 6,7-dimethoxy-3-trichloromethyl-phthalide 

Downstream Products

• 71700-15-7 12b-hydroxy-9,10-dimethoxy-5H-[1,3]dioxolo[4'',5'':4',5']benzo[1',2':4,5]azepino[2,1-a]isoindole-8,13(6H,12bH)-dione 

Relevant articles and documents

Total synthesis of lennoxamine and chilenine via ring-expansion of isoindoloisoquinoline to isoindolobenzazepine

Convenient synthesis of the benzazepine alkaloids, lennoxamine (1) and chilenine (2), is described. The key steps are conversion of methylenelactam (5) to an N-tertiary acyliminium ion precursor (16) and a novel expansion of the six-membered ring of 4 to a benzazepine ring system (3b), which could be transformed into lennoxamine (1) and chilenine (2).