22428-86-0

Basic information

• Product Name: 1,4-DITHIASPIRO[4.5]DECAN-8-OL
• Synonyms: 1,4-DITHIASPIRO[4.5]DECAN-8-OL;LABOTEST-BB LT00112379;8-Hydroxy-1,4-dithiaspiro[4.5]decane;NSC 244358
• CAS NO: 22428-86-0
• Molecular Formula: C₈H₁₄OS₂
• Molecular Weight: 190.33
• Mol File: 22428-86-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 83-85℃
• Boiling Point: 339.7 °C at 760 mmHg
• Flash Point: 165.3 °C
• Appearance: /
• Density: 1.26
• Vapor Pressure: 6.05E-06mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 1,4-DITHIASPIRO[4.5]DECAN-8-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DITHIASPIRO[4.5]DECAN-8-OL(22428-86-0)
• EPA Substance Registry System: 1,4-DITHIASPIRO[4.5]DECAN-8-OL(22428-86-0)

Safety Data

• Hazardous Substances Data: 22428-86-0(Hazardous Substances Data)

Usage

General Description

1,4-Dithiaspiro[4.5]decan-8-ol is a chemical compound with the molecular formula C8H16OS2. It is a colorless to light yellow liquid with a molecular weight of 184.34 g/mol. 1,4-Dithiaspiro[4.5]decan-8-ol is used in the manufacturing of pharmaceuticals and as a building block in organic synthesis. It has an eight-membered spirocyclic ring with two sulfur atoms and a hydroxyl group attached. 1,4-Dithiaspiro[4.5]decan-8-ol is known for its unique chemical structure and is used in various research and industrial applications.

InChI:InChI=1/C8H14OS2/c9-7-1-3-8(4-2-7)10-5-6-11-8/h7,9H,1-6H2

Upstream product

• 54531-77-0 4,4-<1,2-ethanediylbis(thio)>cyclohexyl benzoate 
• 54531-74-7 4,4-<1,2-ethanediylbis(thio)>cyclohexanone 
• 69125-55-9 4-hydroxy-1-methoxy-1-cyclohexene 
• 540-63-6 ethane-1,2-dithiol 
• 150-76-5 4-methoxy-phenol 
• 23510-95-4 4-benzoyloxycyclohexanone 
• 6308-92-5 4-benzoyloxycyclohexanol 
• 637-88-7 1,4-Cyclohexanedione 
• 22428-87-1 4,4-ethylenedioxycyclohexan-1-ol 

Downstream Products

• 54531-74-7 4,4-<1,2-ethanediylbis(thio)>cyclohexanone 
• 83638-29-3 1,4-bis(3,5-dimethoxyphenyl)butane 

Relevant articles and documents

Origin of stereocontrol in the construction of the 12-oxatricyclo[6.3.1. 02,7]dodecane ring system by Prins-pinacol reactions

(Chemical Equation Presented) Polycyclic products containing the 12-oxatricyclo[6.3.1.02,7]dodecane moiety having either the trans (8a-e) or cis (9a-e) relative configuration of the oxacyclic bridge and the cis angular substituents are formed s

An Investigation on Desilylation of Alkyl and Phenolic Silyl Ethers Using FeCl3

A variety of alkyl and phenolic TBDMS ethers have been efficiently cleaved using anhydrous FeCl3 in MeOH under mild conditions. It was found that choice of solvent is crucial for the rate of the deprotection of TBDMS ether with FeCl3.

Annulation of α-Formyl α,β-Unsaturated Ketones by a Michael Addition-Cyclization Sequence. A Versatile Synthesis of Alicyclic Six-Membered Rings.

The potential generality of the annulation sequence shown in Scheme II (10 -> 11 -> 12 -> 13 -> 14/15) has been examined in model systems.Dehydrogenation of α-formylcyclohexanones 11a-d with 1 equiv of DDQ rapidly produces α,β-unsaturated α-formyl ketones