6308-92-5Relevant articles and documents
Synthetic method for cis-1,4-cyclohexanediol
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Paragraph 0055-0059, (2018/03/24)
The invention discloses a synthetic method for cis-1,4-cyclohexanediol, belonging to the field of organic chemical synthesis. According to the method, 4-(alkylacyloxy)cyclohexanone is used as a raw material and is only subjected to reduction and hydrolysis so as to conveniently synthesize cis-1,4-cyclohexanediol. The method can guarantee high selectivity of the reactions, and is high in the yieldof cis-1,4-cyclohexanediol and suitable for large-scale production.
Formation of enehydrazine intermediates through coupling of phenylhydrazines with vinyl halides: Entry into the Fischer indole synthesis
Zhan, Fuxu,Liang, Guangxin
supporting information, p. 1266 - 1269 (2013/03/13)
Cut to the chase: Direct formation of an enehydrazine, an intermediate in the classic Fischer indole synthesis, solves the regioselectivity problem associated with indolization. This approach not only achieves selective synthesis of indoles through proper selection of the vinyl halide, but also leads to quick construction of desoxyeseroline and esermethole, as well as the key structural motif in the Akuammiline alkaloid vincorine. Copyright
CATALYTIC RADIOFLUORINATION
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Page/Page column 97-98, (2010/11/30)
One aspect of the present invention relates to a method of preparing radio fluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, potassium fluoride-18 is used. Another aspect of the invention relates to arylammonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the ammonium compound is a tetraaryl ammonium salt. Another aspect of the invention relates to arylsulfonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the sulfonium compound is a triaryl sulfonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a compound of the invention, and acquiring a positron emission spectrum of the mammal.