23062-41-1

Basic information

• Product Name: 3-bromo-4-phenylthiophene
• CAS NO: 23062-41-1
• Molecular Formula: C₁₀H₇BrS
• Molecular Weight: 239.1316
• Mol File: 23062-41-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 264.8°C at 760 mmHg
• Flash Point: 113.9°C
• Density: 1.49g/cm³
• Vapor Pressure: 0.0156mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 3-bromo-4-phenylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-4-phenylthiophene(23062-41-1)
• EPA Substance Registry System: 3-bromo-4-phenylthiophene(23062-41-1)

Safety Data

• Hazardous Substances Data: 23062-41-1(Hazardous Substances Data)

Usage

General Description

3-bromo-4-phenylthiophene is a chemical compound with the molecular formula C10H7BrS. It is a thiophene derivative that contains a bromine atom and a phenyl group attached to the thiophene ring. 3-bromo-4-phenylthiophene is commonly used as a building block in the synthesis of organic compounds and pharmaceuticals. It is also utilized in various research and development applications, particularly in the field of organic chemistry. 3-bromo-4-phenylthiophene is known for its versatile reactivity and its potential to be modified into a wide range of functionalized thiophene derivatives, making it a valuable compound in the chemical industry.

Upstream product

• 3141-26-2 3,4-dibromothiophene 
• 591-50-4 iodobenzene 
• 500772-23-6 2,4,5-tribromo-3-phenylthiophene 
• 2404-87-7 3-phenylthiophene 
• 19698-46-5 2,5-Dibromo-3-phenylthiophene 
• 98-80-6 phenylboronic acid 
• 872-31-1 3-Bromothiophene 

Downstream Products

• 500772-24-7 3-phenyl-4-[(4-phenylthien-3-yl)thio]thiophene 
• 500772-25-8 3,5-diphenyldithieno[3,2-b:2',3'-d]thiophene 
• 500772-26-9 3,5-diphenyldithieno[3,2-b:2',3'-d]thiophene-4,4-dioxide 
• 500772-27-0 2-bromo-3,5-diphenyl-dithieno[3,2-b:2',3'-d]thiophene-4,4-dioxide 
• 500772-28-1 2-(5-methylthien-2-yl)-3,5-diphenyl-dithieno[3,2-b:2',3'-d]thiophene-4,4-dioxide 
• 500772-29-2 2-bromo-3,5-diphenyl-6-(5-methylthien-2-yl)-dithieno[3,2-b:2',3'-d]thiophene-4,4-dioxide 
• 500772-30-5 2-(5-methylthien-2-yl)-3,5-diphenyl-6-[5-dimethyl(chloromethyl)silylthien-2-yl]dithieno[3,2-b:2',3'-d]thiophene-4,4-dioxide 
• 23062-43-3 8H-Indeno<1,2-c>thiophen-8-on 
• 23062-42-2 4-phenylthiophene-3-carboxylic acid 
• 1361305-92-1 3-(4-hydroxy-3-methylphenyl)-4-phenylthiophene 
• 1361306-24-2 3-(4-methoxy-3-methylphenyl)-4-phenylthiophene 
• 763138-83-6 1,1'-bis-(toluene-4-sulfonyl)-1H,1'H-[3,3']biindolyl 
• 2132-80-1 4,4'-Dimethoxybiphenyl 

Relevant articles and documents

Impregnated palladium on magnetite as catalyst for direct arylation of heterocycles

Palladium impregnated on magnetite is an efficient, cheap and easy to prepare catalyst for the direct arylation of heterocycles. Good yields are afforded under relatively mild conditions and a broad substrate scope is evident. The catalyst is regioselective in many cases, affording arylated products, at the C2- or C3-position (depending of the heterocycle used). The methodology can be extended to prepare chromenes through an intramolecular direct arylation reaction. Some evidence is provided for two catalyst deactivation pathways, which prevents efficient recycling.

Pd/C as a catalyst for completely regioselective c=h functionalization of thiophenes under mild conditions

The completely C3-selective arylation of thiophenes and benzo[b]thiophenes was achieved by using Pd/C as a heterogeneous catalyst without ligands or additives under mild reaction conditions. The practicability of this transformation is demonstrated by notable functional group tolerance and the insensitivity of the reaction to H2O and air. This method is also applicable to nitrogen- and oxygen-containing heterocycles, yielding the corresponding C2-arylated products. Three-phase tests along with Hg-poisoning and hot-filtration tests suggest that the catalytically active species is heterogeneous in nature. I+ can do better! Pd/C can be used without ligands or additives to catalyze the completely C3-selective arylation of diversely substituted thiophenes and benzo[b]thiophenes under mild reaction conditions. The physical nature of the catalytic species was investigated and the mechanism was studied. Relative rate data generated in a "robustness screen" were used to design a complex substrate that undergoes highly chemoselective sequential functionalization. Copyright