259107-28-3

Basic information

• Product Name: 2S,5S,6R-4,5-dimethyl-6-phenyl-2-(1,1-dimethyl-2-methoxy ethyl) morpholin-3-one
• Synonyms: 2S,5S,6R-4,5-dimethyl-6-phenyl-2-(1,1-dimethyl-2-methoxy ethyl) morpholin-3-one
• CAS NO: 259107-28-3
• Molecular Weight: 291.39
• Mol File: 259107-28-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2S,5S,6R-4,5-dimethyl-6-phenyl-2-(1,1-dimethyl-2-methoxy ethyl) morpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2S,5S,6R-4,5-dimethyl-6-phenyl-2-(1,1-dimethyl-2-methoxy ethyl) morpholin-3-one(259107-28-3)
• EPA Substance Registry System: 2S,5S,6R-4,5-dimethyl-6-phenyl-2-(1,1-dimethyl-2-methoxy ethyl) morpholin-3-one(259107-28-3)

Safety Data

• Hazardous Substances Data: 259107-28-3(Hazardous Substances Data)

Upstream product

• 207223-22-1 (2S,5S,6R)-2-Hydroxy-2-isopropyl-4,5-dimethyl-6-phenyl-morpholin-3-one 
• 207223-32-3 (5S,6R)-2-(2-propylidene)-4,5-dimethyl-6-phenylmorpholine-3-one 
• 259107-26-1 8R,6R,9S,5,5,9,10-tetramethyl-1,3,7-trioxa-10-aza-spiro[5,5]undecan-11-one 
• 74-88-4 methyl iodide 
• 55109-47-2 3-methyl-2-oxobutanoyl chloride 
• 299-42-3 ephedrine 
• 696641-89-1 2-((2S,5S,6R)-4,5-Dimethyl-3-oxo-6-phenyl-morpholin-2-yl)-2-methyl-propionic acid ethyl ester 

Downstream Products

• 79-50-5 (S)-pantolactone 

Relevant articles and documents

The synthesis of (S)-( + )-pantolactone and its analogues from an ephedrine-derived morpholinone

An efficient general route for the enantioselective synthesis of (S)-(+)-pantolactone and its analogues has been developed from an ephedrine-derived chiral morpholin-3-one. Selective dialkylation of an ephedrine-derived chiral template without epimerization is the key step in this synthesis.