259794-52-0Relevant articles and documents
Synthesis of 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives and evaluation of their affinity for MHC class-II proteins
Ducry, Laurent,Reinelt, Stefan,Seiler, Paul,Diederich, Francois,Bolin, David R.,Campbell, Robert M.,Olson, Gary L.
, p. 2432 - 2447 (2007/10/03)
1,2,5-Thiadiazolidin-3-one 1,1-dioxide derivatives (±)-1a-d and (±)-2 were designed by molecular modeling as MHC (major histocompatibility complex) class-II inhibitors. They were prepared from the unsymmetrically N,N'- disubstituted acyclic sulfamides (±)