80253-36-7

Basic information

• Product Name: 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid
• Synonyms: 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid
• CAS NO: 80253-36-7
• Molecular Weight: 251.282
• Mol File: 80253-36-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 437.5±38.0 °C(Predicted)
• Density: 1.186±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid(80253-36-7)
• EPA Substance Registry System: 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid(80253-36-7)

Safety Data

• Hazardous Substances Data: 80253-36-7(Hazardous Substances Data)

Upstream product

• 19036-43-2 aminopivalic acid 
• 501-53-1 benzyl chloroformate 
• 26734-09-8 3-amino-2,2-dimethylpropan-1-ol 
• 666844-60-6 benzyl (3-hydroxy-2,2-dimethylpropyl)carbamate 
• 259794-51-9 methyl 2,2-dimethyl-3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate 
• 14002-80-3 Methyl 2,2-dimethyl-3-hydroxypropionate 
• 2843-19-8 3-amino-2,2-dimethylpropanoic acid, hydrochloride salt 

Downstream Products

• 1201096-13-0 C₂₃H₃₅NO₆ 
• 666844-61-7 (2-carbamoyl-2-methylpropyl)carbamic acid benzyl ester 
• 80253-41-4 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivalic acid 
• 80253-44-7 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivalic acid ethyl ester 
• 80253-45-8 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivalic acid 
• 80253-40-3 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivalic acid ethyl ester 
• 80253-39-0 β-benzyloxycarbonylaminopivaloyl-β-aminopivalic acid 
• 259794-60-0 (+/-)-methyl 2-[({[2-(tert-butoxycarbonyl)-2,2-dimethylethyl]amino}sulfonyl)amino]-4-phenylbutanoate 
• 259794-64-4 (+/-)-tert-butyl 2,2-dimethyl-3-[4-(2-phenylethyl)-1,1,3-trioxo-1λ⁶,2,5-thiadiazolan-2-yl]propanoate 
• 259794-53-1 3-amino-2,2-dimethylpropionic acid tert-butyl ester 
• 259794-52-0 tert-butyl 3-{[(benzyloxy)carbonyl]amino}-2,2-dimethylpropanoate 

Relevant articles and documents

SGC STIMULATORS

Compounds of Formulae (I') and (I) are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

PYRAZOLE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF

The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group represented by the general formula: or a group represented by the general formula: while the other represents an optionally substituted C1-6 alkyl group etc.; R2 represents H, a halogen atom, OH, an optionally substituted C1-6 alkyl group etc.; X represents a single bond, O or S; Y represents an optionally substituted C1-6 alkylene group etc.; Z represents -RB, -CORC etc. in which RB represents an optionally substituted C1-6 alkyl group etc.; and RC represents an optionally substituted C1-6 alkyl group etc.,; R4 represents H, an optionally substituted C1-6 alkyl group etc.; and R3, R5 and R6 represent H, a halogen atom etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT1 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, impaired glucose tolerance, impaired fasting glycemia, diabetic complications or obesity, and a disease associated with the increase of blood galactose level such as galactosemia, and pharmaceutical compositions comprising the same, pharmaceutical uses thereof, and intermediates for production thereof.

Benzo-fused lactams that promote the release of growth hormone

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient thereof are also disclosed.