26349-74-6

Basic information

• Product Name: methyl (2R)-(-)-2-isothiocyanatopropanoate
• Synonyms: methyl (2R)-(-)-2-isothiocyanatopropanoate
• CAS NO: 26349-74-6
• Molecular Weight: 145.182
• Mol File: 26349-74-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (2R)-(-)-2-isothiocyanatopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R)-(-)-2-isothiocyanatopropanoate(26349-74-6)
• EPA Substance Registry System: methyl (2R)-(-)-2-isothiocyanatopropanoate(26349-74-6)

Safety Data

• Hazardous Substances Data: 26349-74-6(Hazardous Substances Data)

Upstream product

• 463-71-8 thiophosgene 
• 13515-97-4 methyl 2-aminopropanoate monohydrochloride 

Downstream Products

• 97491-77-5 N-(4--phenyl)-N'-(1-methoxycarbonyl-ethyl)-thioharnstoff 
• 1309465-11-9 (4S,5R)-methyl 5-(4-chlorophenyl)-1-(diphenylphosphinoyl)-4,5-dimethyl-2-thioxoimidazolidine-4-carboxylate 
• 1309465-14-2 (4S,5R)-methyl 1-(diphenylphosphinoyl)-4,5-dimethyl-5-(4-methylphenyl)-2-thioxoimidazolidine-4-carboxylate 
• 1198118-27-2 (4R,5R)-methyl 5-(4-methoxyphenyl)-4,5-dimethyl-2-thioxooxazolidine-4-carboxylate 
• 1198118-22-7 (4R,5R)-methyl 4,5-dimethyl-5-phenyl-2-thioxooxazolidine-4-carboxylate 
• 1198118-32-9 (4R,5R)-methyl 4,5-dimethyl-5-phenyl-2-thioxooxazolidine-4-carboxylate 
• 1309465-19-7 (4S,5S)-methyl 1-(diphenylphosphinoyl)-4,5-dimethyl-5-(2-thienyl)-2-thioxoimidazolidine-4-carboxylate 

Relevant articles and documents

T3P - A Benign Desulfurating Reagent in the Synthesis of Isothiocyanates

A number of alkyl, aryl and bifunctional isothiocyanates are obtained in moderate to high yields (41-94%) in a two-step, one-pot reaction of the parent primary amines or their salts with carbon disulfide, followed by reaction of the thus formed dithiocarbamates with T3P (propane phosphonic acid anhydride) as a new and efficient desulfurating agent.