26547-51-3 Usage
Description
8-Phenyloctanoic acid, an n-phenylalkanoic acid, is an intermediate compound that plays a significant role in supporting bacterial growth. It is characterized by the presence of a phenyl group attached to an octanoic acid chain, which contributes to its unique chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
8-Phenyloctanoic acid is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique structure allows it to be a key component in the development of new drugs and medications, particularly those targeting bacterial infections.
Used in Biotechnology:
In the field of biotechnology, 8-Phenyloctanoic acid is utilized as a growth-supporting agent for specific bacteria, such as Pseudomonas putida. When cultured in a chemically defined medium containing 8-Phenyloctanoic acid, this bacterium can thrive, making it a valuable tool for research and development in biotechnology applications.
Used in Chemical Synthesis:
8-Phenyloctanoic acid is used as a building block in the synthesis of various organic compounds and materials. Its unique structure makes it a versatile component in the creation of new chemicals with potential applications in industries such as plastics, coatings, and adhesives.
Used in Research and Development:
Due to its unique properties and potential applications, 8-Phenyloctanoic acid is often used in research and development settings. Scientists and researchers can leverage its characteristics to explore new avenues in drug development, material science, and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 26547-51-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,5,4 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 26547-51:
(7*2)+(6*6)+(5*5)+(4*4)+(3*7)+(2*5)+(1*1)=123
123 % 10 = 3
So 26547-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H20O2/c15-14(16)12-8-3-1-2-5-9-13-10-6-4-7-11-13/h4,6-7,10-11H,1-3,5,8-9,12H2,(H,15,16)/p-1
26547-51-3Relevant articles and documents
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
González-Gil, Inés,Zian, Debora,Vázquez-Villa, Henar,Hernández-Torres, Gloria,Martínez, R. Fernando,Khiar-Fernández, Nora,Rivera, Richard,Kihara, Yasuyuki,Devesa, Isabel,Mathivanan, Sakthikumar,Del Valle, Cristina Rosell,Zambrana-Infantes, Emma,Puigdomenech, María,Cincilla, Giovanni,Sanchez-Martinez, Melchor,Rodríguez De Fonseca, Fernando,Ferrer-Montiel, Antonio V.,Chun, Jerold,López-Vales, Rubén,López-Rodríguez, María L.,Ortega-Gutiérrez, Silvia
supporting information, p. 2372 - 2390 (2020/01/02)
Neuropathic pain (NP) is a complex chronic pain state with a prevalence of almost 10% in the general population. Pharmacological options for NP are limited and weakly effective, so there is a need to develop more efficacious NP attenuating drugs. Activation of the type 1 lysophosphatidic acid (LPA1) receptor is a crucial factor in the initiation of NP. Hence, it is conceivable that a functional antagonism strategy could lead to NP mitigation. Here we describe a new series of LPA1 agonists among which derivative (S)-17 (UCM-05194) stands out as the most potent and selective LPA1 receptor agonist described so far (Emax = 118%, EC50 = 0.24 μM, KD = 19.6 nM; inactive at autotaxin and LPA2-6 receptors). This compound induces characteristic LPA1-mediated cellular effects and prompts the internalization of the receptor leading to its functional inactivation in primary sensory neurons and to an efficacious attenuation of the pain perception in an in vivo model of NP.
