27332-20-3Relevant articles and documents
Palladium(0)-catalysed regioselective cyclisations of 2-amino(tosyl) benzamides/sulphonamides: The stereoselective synthesis of 3-ylidene-[1,4]benzodiazepin-5-ones/benzo[f][1,2,5]thiadiazepine-1,1-dioxides
Mondal, Debasmita,Pal, Gargi,Chowdhury, Chinmay
, p. 5462 - 5465 (2021/06/09)
The Pd(0) catalysed cyclisation reactions betweentert-butyl propargyl carbonates and 2-aminotosyl benzamides or sulphonamides deliver 1,4-benzodiazepin-5-ones or sultam derivatives, key components of many biologically active compounds. But 2-amino benzamides/sulphonamides require propargyl carbonates substituted at acetylenic carbon to undergo the reaction resulting in the stereoselective formation of the said products.
Transition-Metal-Free Tandem Cyclization/ N-Arylation Reaction: A Method to Access Biaryl Sultam Derivatives via a Diradical Pathway
Thorat, Vijaykumar H.,Hsieh, Jen-Chieh,Cheng, Chien-Hong
, p. 6623 - 6627 (2020/09/02)
A novel procedure for the transition-metal-free tandem cyclization/N-arylation reaction sequence of an aryne with a 1,2,3,4-benzothiatriazine-1,1-dioxide is reported. This reaction goes through the intramolecular homolytic cyclization to generate an N-H b
Dibenzo[1,2,5]thiadiazepines are non-competitive GABAA receptor antagonists
Ramirez-Martinez, Juan F.,Gonzalez-Chavez, Rodolfo,Guerrero-Alba, Raquel,Reyes-Gutierrez, Paul E.,Martinez, Roberto,Miranda-Morales, Marcela,Espinosa-Luna, Rosa,Gonzalez-Chavez, Marco M.,Barajas-Lopez, Carlos
, p. 894 - 913 (2013/03/28)
A new process for obtaining dibenzo[c,f][1,2,5]thiadiazepines (DBTDs) and their effects on GABAA receptors of guinea pig myenteric neurons are described. Synthesis of DBTD derivatives began with two commercial aromatic compounds. An azide group was obtain