2748-98-3Relevant articles and documents
On the synthesis of phaeantharine. I. Plan of the synthesis of phaeantharine and synthesis of the unit A: 4',5-Bis(bromomethyl)-2-methoxydiphenyl ether
Knabe,Weirich
, p. 445 - 449 (1983)
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Total synthesis of polymorphatin A, a macrocyclic bisbibenzyl with boat configured arenes
Almalki, Faisal A.,Sun, Wei,Light, Mark E.,Harrowven, David C.
, (2020/09/04)
Polymorphatin A was reported as a constituent of Marchantia polymorpha in 2007 following much speculation as to its likely existence as a natural product. Interest was rekindled when a claimed total synthesis revealed inconsistencies in spectral data betw
Entropically favorable macrolactamization. Synthesis of isodityrosine peptide analogues by tandem Erlenmeyer condensation-macrolactamization
Bailey,Molinski
, p. 2500 - 2504 (2007/10/03)
Macrolactams containing a modified isodityrosine moiety were assembled by direct addition of a bis-4-aryliden-5(4H)-oxazolone, derived by double Erlenmeyer condensation of diaryl ether dicarboxaldehydes and an α,ω- diamine, derived from the same precursor. Tandem acylation of diamines with the bis-Erlenmeyer oxazolone gave macrolactams in yields of up to 30%. TECM demonstrates an entropically controlled 28-membered ring closure and allows rapid access to a variety of cyclic isodityrosine peptide analogues of the biologically active natural product bastadin-5.
