288252-38-0

Basic information

• Product Name: 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE
• Synonyms: 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE;BUTTPARK 95\50-53
• CAS NO: 288252-38-0
• Molecular Formula: C₁₁H₈Cl₂N₂O
• Molecular Weight: 255.1
• Mol File: 288252-38-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 115 °C
• Boiling Point: 358.7°C at 760 mmHg
• Flash Point: 170.7°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 2.5E-05mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE(288252-38-0)
• EPA Substance Registry System: 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE(288252-38-0)

Safety Data

• Hazard Codes: C:Corrosive
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• Hazardous Substances Data: 288252-38-0(Hazardous Substances Data)

Usage

Description

1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride is a chemical compound with the molecular formula C10H8ClN2O. It is a derivative of pyrazole and contains a chlorine and carbonyl chloride functional group. 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE is known for its reactivity as a chlorinating agent and is widely utilized in various fields.

Uses

Used in Pharmaceutical Industry:
1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride is used as a reagent for the preparation of pharmaceuticals and medicinal compounds. Its application in this industry is due to its reactivity and ability to contribute to the synthesis of various drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride is used as a reagent for the preparation of agrochemicals. Its role in this industry is to aid in the development of compounds that can be used in the agricultural sector for pest control and crop protection.
Used in Dye Industry:
1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride is also used in the dye industry for the preparation of various dyes. 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE's reactivity and functional groups make it suitable for creating a range of dye products.
Used in Materials Science:
In the field of materials science, 1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride is used for the development of new materials and polymers. Its unique properties and reactivity contribute to the creation of innovative materials with potential applications in various industries.

InChI:InChI=1/C11H8Cl2N2O/c1-7-10(11(13)16)6-14-15(7)9-4-2-8(12)3-5-9/h2-6H,1H3

Upstream product

• 187998-35-2 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid 
• 134653-70-6 ethyl 2-[(dimethylamino)methylene]-3-oxobutanoate 
• 169548-94-1 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 

Downstream Products

• 288250-35-1 1-(4-chlorophenyl)-N-(3-cyano-4-piperidinophenyl)-5-methylpyrazole-4-carboxamide 
• 288251-22-9 1-(4-chlorophenyl)-N-{3-cyano-4-[4-(2-hydroxypiperidin-1-yl)piperidin-1-yl]phenyl}-5-methylpyrazole-4-carboxamide 
• 288250-23-7 1-(4-chlorophenyl)-N-{3-cyano-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}-5-methylpyrazole-4-carboxamide 
• 288250-56-6 ethyl 1-{4-[1-(4-chlorophenyl)-5-methyl-4-pyrazolecarboxamide]-2-cyanophenyl}piperidine-4-carboxylate 
• 288250-36-2 tert-butyl 4-{4-[1-(4chlorophenyl)-5-methyl-4-pyrazolecarboxamide]-cyanophenyl}piperazin-1-ylcarboxylate 
• 288250-87-3 1-(4-chlorophenyl)-N-[3-cyano-4-(4-piperidinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide 
• 288250-39-5 1-{4-[1-(4-chlorophenyl)-5-methylpyrazole-4-carboxamide]-2-cyanophenyl}-4-piperidinylbenzoate 
• 288250-47-5 1-(4-chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide 
• 288250-62-4 1-(4-chlorophenyl)-N-{3-cyano-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-5-methylpyrazole-4-carboxamide 
• 288250-60-2 N-(4-{4-[N,N-bis(2-hydroxyethyl)amino]piperidin-1-yl}-3-cyanophenyl)-1-(4-chlorophenyl)-5-methylpyrazole-4-carboxamide 
• 288250-59-9 1-(4-chlorophenyl)-N-{3-cyano-4-[4-(N,N-dimethylamino)piperidin-1-yl]phenyl}-5-methylpyrazole-4-carboxamide 
• 288250-73-7 1-(4-chlorophenyl)-N-(3-cyano-4-pyrrolidinophenyl)-5-methylpyrazole-4-carboxamide 
• 288250-75-9 1-(4-chlorophenyl)-N-(3-cyano-4-homopiperidinophenyl)-5-methylpyrazole-4-carboxamide 
• 288250-53-3 1-(4-chlorophenyl)-N-(3-cyano-4-(4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl)phenyl)-5-methylpyrazole-4-carboxamide 

Relevant articles and documents

AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF

The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): wherein each symbol has the same meaning as defined in the description, or a pharmacologically acceptable salt thereof.

Pyrazole-amides and sulfonamides as sodium channel modulators

Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.

AMIDE COMPOUNDS AND MEDICINAL USE THEREOF

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.