306314-88-5

Basic information

• Product Name: L-Glutamic acid, N-[4-[2-(2-amino-4-methyl-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] -
• CAS NO: 306314-88-5
• Molecular Formula: C21H23N5O5
• Molecular Weight: 425.444
• Mol File: 306314-88-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[4-[2-(2-amino-4-methyl-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] -(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[4-[2-(2-amino-4-methyl-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] -(306314-88-5)
• EPA Substance Registry System: L-Glutamic acid, N-[4-[2-(2-amino-4-methyl-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] -(306314-88-5)

Safety Data

• Hazardous Substances Data: 306314-88-5(Hazardous Substances Data)

Upstream product

• 306314-98-7 diethyl N-{2-pivaloylamino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethynyl]benzoyl}-L-glutamate 
• 306314-96-5 2-pivaloylamino-4-methyl-5-trimethylsilylethynylpyrrolo[2,3-d]pyrimidine 
• 306314-97-6 2-pivaloylamino-4-methyl-5-ethynylpyrrolo[2,3-d]pyrimidine 
• 306314-95-4 2-pivaloylamino-4-methyl-5-iodopyrrolo[2,3-d]pyrimidine 
• 306314-91-0 2-amino-4-methyl-7-(N-benzyl)piperidinyl[2,3-d]pyrimidine 
• 306314-94-3 2-pivaloylamino-4-methylpyrrolo[2,3-d]pyrimidine 
• 306314-92-1 2-amino-4-methyl-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine 
• 306314-90-9 4-chloro-5-(2-chloroethyl)-6-methylpyrimidine 
• 306314-93-2 4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 6940-45-0 5-(2-hydroxyethyl)-6-methyl-2-aminouracil 
• 306314-99-8 diethyl N-{2-pivaloylamino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate 

Relevant articles and documents

Design, synthesis, and x-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent

A novel N-{2-amino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (3a) was designed and synthesized as a potent dual inhibitor of thymidylate synthase (TS) and dihydrofolate reductase (DHFR) and as an antitumor agent. Compound 3b, t