6940-45-0

Basic information

• Product Name: 2-AMINO-6-HYDROXY-5-(B-HYDROXYETHYL)-4-METHYLPYRIMIDINE
• Synonyms: 2-amino-5-(2-hydroxyethyl)-6-methylpyrimidin-4(3H)-one(SALTDATA: FREE);2-Amino-5-(2-hydroxyethyl)-6-methylpyrimidin-4(3H)-one;2-amino-5-(2-hydroxyethyl)-6-methyl-1H-pyrimidin-4-one;BUTTPARK 21\02-92;2-AMINO-6-HYDROXY-5-(B-HYDROXYETHYL)-4-METHYLPYRIMIDINE;2-Amino-5-(2-hydroxy-ethyl)-6-methyl-3H-pyrimidin-4-one
• CAS NO: 6940-45-0
• Molecular Formula: C₇H₁₁N₃O₂
• Molecular Weight: 169.18
• Mol File: 6940-45-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 344.9 °C at 760 mmHg
• Flash Point: 162.4 °C
• Appearance: /
• Density: 1.45 g/cm³
• Vapor Pressure: 4.04E-06mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 2-AMINO-6-HYDROXY-5-(B-HYDROXYETHYL)-4-METHYLPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-HYDROXY-5-(B-HYDROXYETHYL)-4-METHYLPYRIMIDINE(6940-45-0)
• EPA Substance Registry System: 2-AMINO-6-HYDROXY-5-(B-HYDROXYETHYL)-4-METHYLPYRIMIDINE(6940-45-0)

Safety Data

• Hazardous Substances Data: 6940-45-0(Hazardous Substances Data)

Usage

General Description

2-Amino-6-hydroxy-5-(beta-hydroxyethyl)-4-methylpyrimidine is a complex organic compound that belongs to the class of chemicals known as pyrimidines, which are aromatic heterocyclic compounds. This specific chemical is an important component involved in the biosynthesis of thiamine or vitamin B1, crucial for the healthy function of the brain, heart and nervous system. It is known for its aromatic nature and contains functional groups including amino group, hydroxy group and methyl group.

InChI:InChI=1/C7H11N3O2/c1-4-5(2-3-11)6(12)10-7(8)9-4/h11H,2-3H2,1H3,(H3,8,9,10,12)

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 113-00-8 guanidine nitrate 
• 593-85-1 guanidine carbonate 
• 124-46-9 guanidine hydrogen carbonate 
• 50-01-1 guanidine hydrochloride 

Downstream Products

• 21585-10-4 2-amino-5,6-dihydro-4-methylfuro[2,3-d]pyrimidine 
• 942139-45-9 C₃₁H₄₇N₇O₆ 
• 709028-42-2 C₃₁H₄₇N₇O₆ 
• 306314-93-2 4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 306314-92-1 2-amino-4-methyl-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine 
• 306314-91-0 2-amino-4-methyl-7-(N-benzyl)piperidinyl[2,3-d]pyrimidine 
• 306315-03-7 N-(7-benzyl-5-ethynyl-4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropanamide 
• 306315-00-4 2,2-dipivaloylamino-4-methyl-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine 
• 306315-01-5 2,2-dipivaloylamino-4-methyl-5-iodo-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine 
• 306315-02-6 2,2-dipivaloylamino-4-methyl-5-trimethylethynyl-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine 
• 306314-88-5 AAG₁₁₃-161 
• 306314-99-8 diethyl N-{2-pivaloylamino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate 
• 306314-98-7 diethyl N-{2-pivaloylamino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethynyl]benzoyl}-L-glutamate 
• 306315-04-8 diethyl N-{2-pivaloylamino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethynyl-7-(N-benzyl)]benzoyl}-L-glutamate 

Relevant articles and documents

Direct synthesis of 5- and 6-substituted 2-aminopyrimidines as potential non-natural nucleobase analogues

A series of 2-aminopyrimidine derivatives, substituted at 5- and 6-positions, were synthesized. The reaction was carried out in a single step by treatment of the corresponding β-ketoester or β-aldehydoester with guanidine hydrochloride in the presence of K2CO3, in a microwave-assisted method without the requirement of solvent. A unique 1:1 co-crystal structure was obtained which shows that a 6-phenyl-2- aminopyrimidinone forms a strong nucleobase-pair with cytosine, involving three hydrogen bonds. The base-pair was found to be as strong as that of natural guanine:cytosine (G:C), signifying the potential application of the synthesized derivatives. Additionally, we also report a second co-crystal involving 5-isopropyl-6-methyl-2-aminopyrimidinone and cytosine in a 1:1 ratio, which also shows strong base-pairing properties. the Partner Organisations 2014.

HIGH FLOW SUPRAMOLECULAR COMPOUNDS

The present invention relates to a supramolecular compound comprising a low molecular weight, apolar compound, said low molecular weight, apolar compound having a melting point of below 45°C, a molecular weight of about 80 to about 1500 amu and a HLB-valueof lower than 8, said low molecular weight, apolar compound bearing a single 4H-unit per molecule. The supramolecular compound according to the present invention may be used in coating, ink, toner, resin, lacquer, adhesive or glue compositions.