306314-93-2 Usage
Chemical class
pyrrolopyrimidine
Explanation
The compound belongs to the class of pyrrolopyrimidine, which is a group of organic compounds consisting of a pyrrole ring fused to a pyrimidine ring.
Explanation
The core structure of the compound is a pyrrolopyrimidine, which is a heterocyclic aromatic compound formed by the fusion of a pyrrole ring and a pyrimidine ring.
Explanation
The compound has a methyl group (CH3) attached to the 4-position of the pyrrolopyrimidine core, which refers to the fourth carbon atom in the pyrimidine ring.
Explanation
1H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-methyl(9CI) has been studied for its potential as an anti-cancer agent due to its ability to interact with biological targets and inhibit cancer cell growth.
Explanation
The compound may also have potential as a kinase inhibitor, which can help in the treatment of various diseases by inhibiting the activity of kinases, a type of enzyme involved in cellular processes such as cell growth and signaling.
Explanation
The compound's ability to interact with biological targets may also make it useful in the treatment of other diseases, although further research is needed to determine its specific applications.
Explanation
It is important to handle 1H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-methyl(9CI) with care and follow safety guidelines, as it may have toxic or harmful effects if not used properly.
Core structure
pyrrolopyrimidine
Methyl group position
4-position
Potential pharmaceutical use
anti-cancer agent
Potential pharmaceutical use
kinase inhibitor
Potential use
treatment of other diseases
Safety precautions
toxic or harmful effects
Check Digit Verification of cas no
The CAS Registry Mumber 306314-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,3,1 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 306314-93:
(8*3)+(7*0)+(6*6)+(5*3)+(4*1)+(3*4)+(2*9)+(1*3)=112
112 % 10 = 2
So 306314-93-2 is a valid CAS Registry Number.
306314-93-2Relevant articles and documents
Compound with 2-aminopyrimidine structure as well as preparation method and purpose thereof
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Paragraph 0301-0304, (2019/06/08)
The invention provides a compound of a 2-aminopyrimidine structure shown as a general formula (1), or a stereisomer, enantiomers or medically acceptable salt of the compound, a preparation method of the compound, a medicine composition containing the composition or a purpose of the composition. The compound shown as the general formula (1) can be used for preparing NIK kinase inhibitors, and can be used for preventing and/or treating diseases relevant to NIK kinase, particularly cancer and metabolic diseases, such as B-cell dysfunction related cancer such as multiple myeloma, lymphocyte carcinoma, diffuse large B cell lymphoma of liver cancer, hodgkin lymphoma and chronic lymphocytic leukemia, prostatic cancer, liver cancer, intestinal cancer, medicine induced liver damage, alcohol inducedliver damage, toxic induced acute liver injury, chronic liver inflammation and the like. The general formula (1) is shown in the description.
Design, synthesis, and x-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent
Gangjee,Yu,McGuire,Cody,Galitsky,Kisliuk,Queener
, p. 3837 - 3851 (2007/10/03)
A novel N-{2-amino-4-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (3a) was designed and synthesized as a potent dual inhibitor of thymidylate synthase (TS) and dihydrofolate reductase (DHFR) and as an antitumor agent. Compound 3b, t
