31060-10-3

Basic information

• Product Name: (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide
• Synonyms: (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide
• CAS NO: 31060-10-3
• Molecular Weight: 245.645
• Mol File: 31060-10-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide(31060-10-3)
• EPA Substance Registry System: (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide(31060-10-3)

Safety Data

• Hazardous Substances Data: 31060-10-3(Hazardous Substances Data)

Upstream product

• 90-82-4 pseudoephedrine 
• 321-98-2 (1S,2R)-(+)-ephedrine 
• 24221-86-1 (+)-(1S,2R)-ephedrine hydrochloride 

Downstream Products

• 130854-70-5 (2R,4R,5R)-2-(2,5-Dimethoxyphenyl)-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 
• 130854-69-2 (2R,4R,5R)-3,4-Dimethyl-2-(2-hydroxy-5-methoxyphenyl)-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 
• 195434-00-5 (E)-(R)-2-((2S,4S,5S)-3,4-Dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-2-((E)-3-phenyl-allyl)-pent-3-enenitrile 
• 195434-04-9 (S)-2-Benzyl-2-((2S,4S,5S)-3,4-dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-pentanenitrile 
• 195433-99-9 (E)-(R)-2-Benzyl-2-((2S,4S,5S)-3,4-dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-pent-3-enenitrile 
• 195434-01-6 (E)-(R)-2-Allyl-2-((2S,4S,5S)-3,4-dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-pent-3-enenitrile 
• 195434-03-8 (R)-2-((2S,4S,5S)-3,4-Dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-2-ethyl-pentanenitrile 
• 195433-98-8 (E)-(R)-2-((2S,4S,5S)-3,4-Dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-2-ethyl-pent-3-enenitrile 
• 195433-96-6 (E)-2-((2S,4S,5S)-3,4-Dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yloxy)-pent-3-enenitrile 
• 130854-68-1 (2R,4R,5S)-3,4-Dimethyl-2-(4-methoxyphenoxy)-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 
• 130762-54-8 (2S,4R,5S)-3,4-Dimethyl-2-(4-methoxyphenoxy)-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 

Relevant articles and documents

Asymmetric Addition of Trimethylsilyl Cyanide to Benzaldehydes Catalyzed by Samarium(III) Chloride and Chiral Phosphorus(V) Reagents

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The Stereochemistry of the Aryl Phosphate/Aryl Phosphonate Rearrangement in 1,3,2-Oxazaphospholidine 2-Oxides

On treatment with LDA/THF (aryloxy)phospholidines in the pseudoephedrine/ephedrine series undergo P-O to P-C rearrangement to afford arylphospholidines with retention of configuration at phosphorus.The stereochemistry of each product was assigned by 1H NM