3220-49-3

Basic information

• Product Name: Phenylcopper(I)
• Synonyms: Phenylcopper(I);Phenylcopper
• CAS NO: 3220-49-3
• Molecular Formula: C₆H₅*Cu
• Molecular Weight: 0
• Mol File: 3220-49-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Phenylcopper(I)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylcopper(I)(3220-49-3)
• EPA Substance Registry System: Phenylcopper(I)(3220-49-3)

Safety Data

• Hazardous Substances Data: 3220-49-3(Hazardous Substances Data)

Usage

General Description

Phenylcopper(I) is a chemical compound with the formula CuC6H5, consisting of a copper ion bonded to a phenyl group. It is a reactive organometallic compound that is commonly used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Phenylcopper(I) is a powerful nucleophile, readily donating its lone pair of electrons to electrophilic carbon atoms, enabling the formation of new chemical bonds. It is also used as a catalyst in various chemical reactions, such as the Grignard reaction and the Barbier reaction. However, phenylcopper(I) is highly air and moisture sensitive, and must be handled and stored under inert conditions to prevent degradation.

Upstream product

• 16002-63-4 phenylmagnesium iodide 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 108-88-3 toluene 
• 71-43-2 benzene 
• 7787-70-4 copper(I) bromide 
• 100-58-3 phenylmagnesium bromide 
• 591-50-4 iodobenzene 
• 7681-65-4 copper(l) iodide 
• 591-51-5 phenyllithium 

Downstream Products

• 98-95-3 nitrobenzene 
• 71-43-2 benzene 
• 91-01-0 1,1-Diphenylmethanol 
• 92-52-4 biphenyl 
• 93-98-1 N-phenyl benzoyl amide 
• 25226-98-6 trans-cinnamaldehyde diethylacetal 
• 57044-78-7 (2-ethyl-hex-1(E)-enyl)-benzene 
• 2901-28-2 ethyl α-phenylhexanoate 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 58202-54-3 (E)-1-(Ethansulfonyl)-2-phenyl-1-hexen 
• 26189-62-8 phenyl 2,2-diphenylethenyl sulfone 
• 108643-81-8 Trimethyl-(3-phenyl-cyclohex-1-enyloxy)-silane 
• 69849-77-0 trimethyl((3-phenylcyclopent-1-en-1-yl)oxy)silane 
• 20795-53-3 3-phenylcyclohexanone 

Relevant articles and documents

High yielding electrophilic amination method for arylcopper reagents

The facilitative effect of some P-, N-, S-, and O-donor ligands in the reaction of arylcoppers with acetone O-(mesitylenesulfonyl)oxime was examined to develop a synthesis method for functionalized primary aryl amines under mild reaction conditions. Our research showed that electrophilic amination of monoaryl coppers with ketoximes can be facilitated using appropriate ligand to supply significant increase in the yield. Also, we have seen that this ligand-facilitated method is applicable in terms of arylcopper and ketoxime type and allows synthesis of primary aryl amines in good to high yields easily at room temperature in very short reaction time.

METHOD FOR PRODUCING BORATE SALT

PROBLEM TO BE SOLVED: To provide a method for producing borate salt which makes it possible to obtain borate salt with different groups bound to boron atoms in high yield. SOLUTION: The present invention provides a method for producing borate salt (A) represented by general formula (1), including the steps for making a reaction occur between borate salt (B) represented by general formula (2) and organic metal compound (C) represented by general formula (3) or general formula (4). SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Highly effective copper-mediated gem-difluoromethylenation of arylboronic acids

A copper-mediated gem-difluoromethylenation of aryl, heteroaryl and vinyl boronic acids with bromodifluoromethylated oxazole or thiazole derivatives has been developed. This novel reaction showed an excellent functional group tolerance and wide substrate scope, providing facile access to practical application in drug discovery and development. the Partner Organisations 2014.