335592-60-4

Basic information

• Product Name: Carbamic acid, [1-methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]- , 1,1-dimethylethyl ester
• CAS NO: 335592-60-4
• Molecular Formula: C20H32BNO4
• Molecular Weight: 361.289
• Mol File: 335592-60-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [1-methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]- , 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [1-methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]- , 1,1-dimethylethyl ester(335592-60-4)
• EPA Substance Registry System: Carbamic acid, [1-methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]- , 1,1-dimethylethyl ester(335592-60-4)

Safety Data

• Hazardous Substances Data: 335592-60-4(Hazardous Substances Data)

Upstream product

• 214973-83-8 tert-butyl (2-(4-bromophenyl)propan-2-yl)carbamate 
• 73183-34-3 bis(pinacol)diborane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 17797-12-5 1-(4-bromophenyl)-1-methylethylamine 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 101184-73-0 2-(4-bromophenyl)-2-methylpropanenitrile 
• 850144-81-9 4-(1-aminocarbonyl-1-methylethyl)-1-bromobenzene 

Downstream Products

• 335592-59-1 4-[4-(1-tert-butoxycarbonylamino-1-methylethyl)phenyl]-2,5-dichloropyrimidine 
• 850360-93-9 1-acetyl-5-[4-(1-tert-butoxycarbonylamino-1-methylethyl)phenyl]-1H-indazole 
• 850360-99-5 1-tert-butoxycarbonyl-5-[4-(1-tert-butoxycarbonylamino-1-methylethyl)phenyl]-4-nitro-1H-indazole 
• 1431551-92-6 tert-butyl (2-(4'-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)-[1,1'-biphenyl]-4-yl)propan-2-yl)carbamate 
• 335592-43-3 4-[4-(1-tertbutoxycarbonylamino-1-methylethyl)phenyl]-5-chloro-N-[4-(2-hydroxyethyl)phenyl]pyrimidine-2-amine 
• 937366-50-2 C₂₄H₂₆BrClN₄O₂ 

Relevant articles and documents

SUBSTITUTED PYRAZOLE COMPOUNDS AS TOLL RECEPTOR INHIBITORS

Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein G, A, R1, and R5 are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

PHARMACEUTICALLY ACTIVE COMPOUNDS

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed.

Protective Agent for Retinal Neuronal Cell Comprising Indazole Derivative as Active Ingredient

As a result of intensive studies for the purpose of finding a new medicinal use of an indazole derivative, it was found that an indazole derivative inhibits glutamate-induced retinal neuronal cell death in rat fetal retinal neuronal cells, in other words, the indazole derivative acts directly on the retinal neuronal cells and exhibits an effect of protecting retinal neuronal cells. Accordingly, the indazole derivative is useful for the prevention or treatment of an eye disease associated with retinal neuronal cell damage or retinal damage.