343864-02-8

Basic information

• Product Name: N-METHYLPIPERAZINE-3,3,5,5-D4
• Synonyms: N-METHYLPIPERAZINE-3,3,5,5-D4;N-Methylpiperazine--d4
• CAS NO: 343864-02-8
• Molecular Formula: C5H8D4N2
• Molecular Weight: 104.19
• Mol File: 343864-02-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-METHYLPIPERAZINE-3,3,5,5-D4(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYLPIPERAZINE-3,3,5,5-D4(343864-02-8)
• EPA Substance Registry System: N-METHYLPIPERAZINE-3,3,5,5-D4(343864-02-8)

Safety Data

• Hazardous Substances Data: 343864-02-8(Hazardous Substances Data)

Usage

Description

N-METHYLPIPERAZINE-3,3,5,5-D4, with the CAS number 343864-02-8, is an isotopically labeled research compound that is utilized in various scientific studies and experiments. It is a derivative of piperazine, a heterocyclic compound, and is characterized by the presence of deuterium atoms, which are isotopes of hydrogen. N-METHYLPIPERAZINE-3,3,5,5-D4 is valuable for its unique properties and potential applications in research and development.

Uses

Used in Research and Development:
N-METHYLPIPERAZINE-3,3,5,5-D4 is used as an isotopically labeled compound for various research purposes. The incorporation of deuterium atoms in the molecule allows for the study of its behavior and interactions in different experimental conditions, providing valuable insights into its properties and potential applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, N-METHYLPIPERAZINE-3,3,5,5-D4 is used as a research compound to aid in the development of new drugs and therapies. Its unique properties and isotopically labeled nature make it an ideal candidate for studying the mechanisms of action, pharmacokinetics, and pharmacodynamics of potential drug candidates.
Used in Chemical Synthesis:
N-METHYLPIPERAZINE-3,3,5,5-D4 is also used as a starting material or intermediate in the synthesis of various chemical compounds. Its isotopically labeled nature can be advantageous in tracking the progress of chemical reactions and understanding the reaction mechanisms, which is crucial for optimizing synthetic routes and improving the overall efficiency of the process.
Used in Analytical Chemistry:
In analytical chemistry, N-METHYLPIPERAZINE-3,3,5,5-D4 can be employed as a reference material or internal standard for the accurate quantification and identification of similar compounds. The presence of deuterium atoms in the molecule can enhance the sensitivity and specificity of analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, leading to more reliable and accurate results.
Used in Environmental Studies:
N-METHYLPIPERAZINE-3,3,5,5-D4 can also be utilized in environmental research to study the fate and transport of similar compounds in the environment. Its isotopically labeled nature can help researchers understand the behavior of these compounds in various environmental matrices, such as soil, water, and air, and their potential impact on ecosystems and human health.

Upstream product

• 60725-35-1 1-methylpiperazine-3,5-dione 
• 4408-64-4 N-methyliminodiacetic acid 
• 109-01-3 1-methyl-piperazine 
• 16339-07-4 1-methyl-4-nitroso-piperazine 
• 1126621-86-0 tert-butyl (2,2,3,3,5,5,6,6-(²H₈))piperazine-1-carboxylate 
• 1189436-83-6 1-(tert-butoxycarbonyl)-4-methyl-(2,2,3,3,5,5,6,6-d₈)piperazine 

Relevant articles and documents

DEUTERIUM-MODIFIED BRIGATINIB DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND USE THEREOF

The present invention relates to the field of pharmaceutical chemistry, and relates to a deuterium-modified Brigatinib derivative, preparation method thereof, pharmaceutical composition containing the same and the uses of the deuterium-modified Brigatinib derivative and the pharmaceutical composition thereof in preparing a medicament for treating the disease mediated by anaplastic lymphoma kinase. The deuterium-modified Brigatinib derivative of the present invention has an excellent inhibitory activity on anaplastic lymphoma kinase and has better pharmacodynamic or pharmacokinetic properties relative to Brigatinib.

Indole ketone compound or its derivatives and their use

The present invention relates to indolone compounds shown by general formula (a) or derivatives thereof, and uses thereof. The technical problem solved by the present invention is to provide indolone compounds or derivatives thereof, and uses thereof. The present invention uses a deuterium-enriched indolone compound obtained from a deuterium-substituted indolone compound. The above-mentioned indolone compounds can simultaneously effect on three key receptor families involved in the process of blood vessel formation, i.e., vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR), and platelet-derived growth factor receptor (PDGFR), and inhibit the formation of blood vessel, thereby achieving the effect of treating cancers. The above-mentioned deuterium-substituted indolone compounds or derivatives thereof have the advantage of high efficiency as medicaments.