3448-42-8

Basic information

• Product Name: (+/-)-phenethylsuccinic acid
• Synonyms: (+/-)-phenethylsuccinic acid
• CAS NO: 3448-42-8
• Molecular Weight: 222.241
• Mol File: 3448-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-phenethylsuccinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-phenethylsuccinic acid(3448-42-8)
• EPA Substance Registry System: (+/-)-phenethylsuccinic acid(3448-42-8)

Safety Data

• Hazardous Substances Data: 3448-42-8(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 10034-85-2 hydrogen iodide 
• 5469-48-7 phenethyl-fumaric acid 
• 5469-48-7 (2-phenylethyl)fumaric acid 
• 131156-36-0 dimethyl 2-(2-phenylethyl)succinate 
• 6125-24-2 2-Phenylnitroethane 

Downstream Products

• 105908-37-0 3-phenethyl-pyrrolidine-2,5-dione 
• 100519-02-6 phenethyl-succinic acid-anhydride 
• 4028-40-4 D-phenethylsuccinic acid 
• 3448-42-8 L-phenethylsuccinic acid 
• 100193-37-1 (4-nitro-phenethyl)-succinic acid 
• 92828-43-8 2-(2-phenylethyl)butanedioic acid, 4-mono(1,1-dimethylethyl)ester 
• 131156-36-0 dimethyl 2-(2-phenylethyl)succinate 

Relevant articles and documents

Nitroalkanes and dimethyl maleate as source of 3-alkyl succinic anhydrides and (E)-3-alkylidene succinic anhydrides

Nitroalkanes react with dimethyl maleate giving a tandem Michael addition/elimination of nitrous acid. The obtained (E)-2-alkylidene dimethyl succinates are: (i) reduced to the corresponding 2-alkyl dimethyl succinates which after hydrolysis produce 1,4-dicarboxylic acids that are prone to convert into the corresponding 3-alkyl succinic anhydrides or (ii) hydrolysed to (E)-2-alkylidene-succinic acids that are easily cyclised to (E)-3-alkylidene succinic anhydrides.