5469-48-7 Usage
General Description
(2E)-2-(2-phenylethyl)but-2-enedioic acid, also known as fumaric acid, is a chemical compound with the molecular formula C10H10O4. It is an organic acid that is naturally found in various fruits and vegetables, and is also used as a food additive and in the production of certain polymers. Fumaric acid has a sour taste and is often used as a flavor enhancer in foods and beverages. It also has various industrial applications, including as a component in the production of resins, plastics, and pharmaceuticals. Additionally, fumaric acid has been studied for its potential therapeutic effects, including its use as a treatment for psoriasis and other skin conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5469-48-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5469-48:
(6*5)+(5*4)+(4*6)+(3*9)+(2*4)+(1*8)=117
117 % 10 = 7
So 5469-48-7 is a valid CAS Registry Number.
5469-48-7Relevant articles and documents
Asymmetric synthesis of 2-substituted butane-1,4-diols by hydrogenation of homochiral fumaramide derivatives
Jawaid, Samaila,Farrugia, Louis J.,Robins, David J.
, p. 3979 - 3988 (2007/10/03)
Diastereoselective hydrogenation of homochiral fumaramides 1 derived from (2R)-Oppolzer's sultam was observed by analysis of the 1H NMR spectra of the succinamide mixtures with de's of 77-88%. Reduction of these succinamides using LiAlH4 gave the corresponding (2S)-butane-1,4- diols and established that addition of hydrogen takes place selectively on the re-face of fumaramides 1. The stereoselectivity was confirmed by estimating the ee's from the 19F NMR spectra of the Mosher's diesters of the diols. This methodology was applied to the synthesis of selected pyrrolidine natural products in homochiral form.
