351075-64-4

Basic information

• Product Name: (2R,4R)-α,α-diphenyl-4-methylazetidine-2-methanol
• Synonyms: (2R,4R)-α,α-diphenyl-4-methylazetidine-2-methanol
• CAS NO: 351075-64-4
• Molecular Weight: 253.344
• Mol File: 351075-64-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4R)-α,α-diphenyl-4-methylazetidine-2-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-α,α-diphenyl-4-methylazetidine-2-methanol(351075-64-4)
• EPA Substance Registry System: (2R,4R)-α,α-diphenyl-4-methylazetidine-2-methanol(351075-64-4)

Safety Data

• Hazardous Substances Data: 351075-64-4(Hazardous Substances Data)

Upstream product

• 351075-59-7 (2R,4S)-2-(acetoxymethyl)-1-benzyl-4-(methanesulfonyloxy)methylazetidine 
• 351075-49-5 (2S,4R)-4-acetoxymethyl-1-benzylazetidine-2-methanol 
• 351075-62-2 methyl (2R,4R)-1-t-butoxycarbonyl-4-methylazetidine-2-carboxylate 
• 351075-60-0 (2R,4R)-1-benzyl-4-methylazetidine-2-methanol 
• 351075-61-1 (2R,4R)-1-t-butoxycarbonyl-4-methylazetidine-2-methanol 
• 174309-28-5 2,4-diethyl (2R,4S)-1-benzylazetidine-2,4-dicarboxylate 
• 127310-66-1 ((2R,4S)-1-benzylazetidine-2,4-diyl)dimethanol 
• 870-78-0 2,4-dibromoglutaric acid diethyl ester 
• 351075-63-3 (2R,4R)-1-(t-butoxycarbonyl)-α,α-diphenyl-4-methylazetidine-2-methanol 

Relevant articles and documents

Synthesis of chiral non-racemic azetidines by lipase-catalysed acetylations and their transformation into amino alcohols: Precursors of chiral catalysts

Azetidinic mono-acetate 7, diol 6b and di-acetate 10a were prepared with high e.e. using PPL-catalysed acetylations. The absolute configurations of all new enantioenriched compounds were assigned by chemical correlation with known compounds. Mono-acetate 7 was then transformed into 30, an amino alcohol of noteworthy potential interest since it represents an interesting precursor for chiral catalysts, such as 32.