365-54-8

Basic information

• Product Name: 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID
• Synonyms: 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID
• CAS NO: 365-54-8
• Molecular Formula: C₁₃H₁₀FNO₂
• Molecular Weight: 231.2224032
• Mol File: 365-54-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID(365-54-8)
• EPA Substance Registry System: 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID(365-54-8)

Safety Data

• Hazardous Substances Data: 365-54-8(Hazardous Substances Data)

Upstream product

• 2252-51-9 2-choro-4-fluorobenzoic acid 
• 62-53-3 aniline 
• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 321-53-9 3-fluoroacridin-9(10H)-one 
• 591-50-4 iodobenzene 
• 446-32-2 4-fluoroanthranilic acid 
• 56096-89-0 4-fluoro-2-iodobenzoic acid 

Downstream Products

• 1080675-70-2 4-fluoro-N-methoxy-N-methyl-2-phenylamino-benzamide 
• 1080675-71-3 1-(4-fluoro-2-phenylamino-phenyl)-propenone 
• 1080675-72-4 1-(4-fluoro-2-phenylamino-phenyl)-3-(4-methanesulfonyl-piperidin-1-yl)-propan-1-one 
• 1080674-54-9 7-fluoro-3-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 
• 1080674-85-6 C₂₃H₂₄FN₃O₅S 
• 1080674-80-1 C₂₂H₂₁FN₂O₄ 
• 1080674-91-4 C₂₃H₂₃FN₂O₅S 
• 1080674-92-5 C₂₃H₂₃FN₂O₅S 
• 1418026-08-0 7-methoxy-3-methyl-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 
• 1418026-11-5 7-fluoro-3-methyl-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 
• 1418026-09-1 3-azidomethyl-7-methoxy-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 
• 1418026-12-6 3-azidomethyl-7-fluoro-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 
• 1418026-10-4 3-aminomethyl-7-methoxy-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester hydrochloride 

Relevant articles and documents

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Light-Driven Intramolecular C?N Cross-Coupling via a Long-Lived Photoactive Photoisomer Complex

Reported herein is a visible-light-driven intramolecular C?N cross-coupling reaction under mild reaction conditions (metal- and photocatalyst-free, at room temperature) via a long-lived photoactive photoisomer complex. This strategy was used to rapidly prepare the N-substituted polycyclic quinazolinone derivatives with a broad substrate scope (>50 examples) and further exploited to synthesize the natural products tryptanthrin, rutaecarpine, and their analogues. The success of gram-scale synthesis and solar-driven transformation, as well as promising tumor-suppressing biological activity, proves the potential of this strategy for practical applications. Mechanistic investigations, including control experiments, DFT calculations, UV-vis spectroscopy, EPR, and X-ray single-crystal structure of the key intermediate, provides insight into the mechanism.

AMINOMETHYL QUINOLONE COMPOUNDS

The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula (I): wherein the variables ar