39507-06-7

Basic information

• Product Name: Benzeneacetic acid, 2-(phenylamino)-, methyl ester
• CAS NO: 39507-06-7
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol File: 39507-06-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 2-(phenylamino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2-(phenylamino)-, methyl ester(39507-06-7)
• EPA Substance Registry System: Benzeneacetic acid, 2-(phenylamino)-, methyl ester(39507-06-7)

Safety Data

• Hazardous Substances Data: 39507-06-7(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 3335-98-6 1-phenyl-1,3-dihydro-indol-2-one 
• 74-88-4 methyl iodide 
• 353497-35-5 2-[(methoxycarbonyl)phenylamino]benzeneacetic acid 
• 805236-74-2 [2-(methoxycarbonyl-phenyl-amino)-phenyl]-acetic acid methyl ester 

Downstream Products

• 731851-81-3 {2-[Phenyl-(2,2,2-trifluoro-acetyl)-amino]-phenyl}-acetic acid 
• 731851-78-8 [2-(benzyl-phenyl-amino)-phenyl]-acetic acid 
• 731851-92-6 (2-phenylamino-phenyl)-acetic acid benzyl ester 
• 731851-88-0 [2-(acetyl-phenyl-amino)-phenyl]-acetic acid 
• 353497-31-1 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxylic acid methyl ester 
• 70172-33-7 2-[2-(phenylamino)phenyl]acetic acid 
• 28721-09-7 10-methoxy-5H-dibenz[b,f]azepine-5-carboxamide 
• 4698-11-7 10-methoxy-5H-dibenzo[b,f]azepine 
• 21737-58-6 10,11-dihydro-5H-dibenzo[b,f]azepin-10-one 
• 3335-98-6 1-phenyl-1,3-dihydro-indol-2-one 
• 28721-07-5 oxcarbazepine 
• 805236-74-2 [2-(methoxycarbonyl-phenyl-amino)-phenyl]-acetic acid methyl ester 

Relevant articles and documents

A new industrial process for oxcarbazepine

A novel industrial process for the antiepileptic drug oxcarbazepine 1 has been developed. Unlike the old process, the new process is free from halogenated solvents and can be performed in standard production equipment. It starts from commercially available 1,3-dihydro-1-phenyl-2H-indol-2-one 10. In the key step, an electrophilic ring closure reaction of 2-[(methoxycarbonyl)phenylamino] benzeneacetic acid 5 to 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxylic acid methyl ester 6 in poly phosphoric acid was applied. For the manufacture of 5, a highly efficient process using a dianion strategy was developed.