397-54-6

Basic information

• Product Name: 2-(4-FLUOROPHENYL)BENZOXAZOLE
• Synonyms: 2-(4-FLUORO-PHENYL)-BENZOOXAZOLE;2-(4-FLUOROPHENYL)BENZOXAZOLE;Benzoxazole, 2-(4-fluorophenyl)-Benzoxazole, 2-(p-fluorophenyl)- (7CI,8CI)
• CAS NO: 397-54-6
• Molecular Formula: C₁₃H₈FNO
• Molecular Weight: 213.21
• Mol File: 397-54-6.mol
• Article Data: 102

Chemical Properties

• Boiling Point: 291.1 °C at 760 mmHg
• Flash Point: 129.9 °C
• Appearance: /
• Density: 1.261 g/cm³
• CAS DataBase Reference: 2-(4-FLUOROPHENYL)BENZOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROPHENYL)BENZOXAZOLE(397-54-6)
• EPA Substance Registry System: 2-(4-FLUOROPHENYL)BENZOXAZOLE(397-54-6)

Safety Data

• Hazardous Substances Data: 397-54-6(Hazardous Substances Data)

Usage

Type of compound

Benzoxazole derivative

Contains

Fluorophenyl group

Field of use

Organic chemistry

Application 1

Fluorescent dye for biological imaging

Application 2

Precursor in the synthesis of novel materials

Pharmaceutical potential

Antitumor agent

Pharmaceutical potential

Probe for detecting specific cellular components

Useful for

Research and industrial applications

Key property

Fluorescent properties

Upstream product

• 456-22-4 4-Fluorobenzoic acid 
• 95-55-6 2-amino-phenol 
• 838-55-1 N-(2-chlorophenyl)-4-fluorobenzamide 
• 671-13-6 N-(2-bromophenyl)-4-fluorobenzamide 
• 403-43-0 4-fluorobenzoyl chloride 
• 95-51-2 o-chloroaniline 
• 615-36-1 2-bromoaniline 
• 273-53-0 benzoxazole 
• 352-34-1 4-fluoro-1-iodobenzene 
• 366-63-2 4-fluoro-N-phenylbenzamide 
• 1582-01-0 4-fluorophenyl tosylate 
• 1207429-53-5 4-fluorophenyl 1H-imidazole-1-sulfonate 
• 136138-52-8 4-fluoro-N-(2-iodophenyl)benzamide 
• 33715-53-6 triethoxy(4-fluorophenyl)silane 

Downstream Products

• 99966-75-3 2-(4-fluorophenyl)benzoxazole dimer 
• 1260140-58-6 2-(10-fluoro-1,2,3,4,5,6,7,8-octaphenylanthracen-9-yl)benzoxazole 
• 1315571-17-5 6-chloro-2-(4-fluorophenyl)benzo[d]oxazole 
• 1325241-86-8 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(4-fluorophenyl)benzoxazole 
• 1226069-30-2 6-bromo-2-(4-fluorophenyl)benzo[d]oxazole 
• 1415419-81-6 2-{[2-(4-chlorobenzoyl)-4-fluoro]phenyl}benzoxazole 

Relevant articles and documents

Novel carbazole-based multifunctional materials with a hybridized local and charge-transfer excited state acting as deep-blue emitters and phosphorescent hosts for highly efficient organic light-emitting diodes

In this work, two carbazole- and benzo[d]oxazole-based novel multifunctional materials with a hybridized local and charge-transfer (HLCT) characteristic, namely,OCIandOCT, which could act as deep-blue fluorophors and phosphorescent hosts, were first desig

Carbazole-based organic electroluminescent material and application thereof in devices

The invention relates to the technical field of organic electroluminescent devices, in particular to a carbazole-based organic electroluminescent material and application thereof in an organic electroluminescent device. The organic electroluminescent mate

Delivering 2-Aryl Benzoxazoles through Metal-Free and Redox-Neutral De-CF3Process

An unexpected cleavage of the Csp3-CF3 bond of CF3-hydrobenzoxazoles has been disclosed, affording a range of 2-aryl benzoxazoles under metal-free and redox-neutral conditions. This transformation has demonstrated broad substrate scope and good compatibility of functional groups. 2-Aryl benzothiazole and 2-aryl benzoimidazole could be smoothly assembled in the same manner. On the basis of preliminary mechanistic studies, base initiated and aromatization driven β-carbon elimination was considered to be the key step for the formation of 2. This reaction offers an alternative, facile, and sustainable route to access important 2-aryl benzoxazole motifs.